Mitochondrial DNA diversity of the Amerindian populations living in the Andean Piedmont of Bolivia: Chimane, Moseten, Aymara and Quechua

Corella, Alfons; Bert, Francesc; Pérez‐Pérez, Alejandro; Gené, M.; Turbón, Daniel

doi:10.1080/03014460601075819

Cited by 25 publications

(33 citation statements)

References 34 publications

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“…Contemporary Amerindians from Atacama have shown 62.5-72.0% of haplogroup B. [35][36][37] To clarify the origin and past dissemination of this retrovirus, extensive genetic analysis of a number of HTLV-1s isolated from diverse geographic regions has been conducted. Some studies support the hypothesis that the dissemination of HTLV-1 from Africa to the New World 11,16 occurred during the slave trade time around sixteenth to nineteenth centuries.…”

Section: Discussionmentioning

confidence: 99%

HTLV Type 1 Genetic Types among Native Descendants in Argentina

Gastaldello

Iñiguez

Otsuki

et al. 2008

AIDS Research and Human Retroviruses

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The province of San Salvador de Jujuy, located in the northwest of Argentina, is a highly endemic area for HTLV-1 infection and a foci of tropical spastic paraparesis/HTLV-1-associated myelopathy (HAM/TSP). Therefore, to better understand this, we carried out a genetic characterization of a large set of HTLV-1 strains (n = 65) of descendants of Amerindians from this region. The LTR and env regions were analyzed. The genetic analysis showed that all of these new HTLV-1 isolates from Argentina belong to the Transcontinental subgroup A of the HTLV-1a Cosmopolitan subtype, with the exception of three isolates that cluster within the Japanese subgroup B. Interestingly, the majority of the sequences from Jujuy province belonged to a distinct cluster within the Latin America Transcontinental subgroup, referred to here as the Jujuy subcluster, and were characterized by specific signatures in the LTR. Given that the samples analyzed in this study belong to the Amerindian population and the high prevalence of HTLV-1 in Jujuy in contrast to the low prevalence of this virus in the country, it could be that HTLV-1aA was spread in Argentina from the Amerindians to the cosmopolitan population. Moreover, this is the first report of an HTLV-1aB or Japanese subgroup in descendants of non-Japanese people in South America.

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Section: Discussionmentioning

confidence: 99%

HTLV Type 1 Genetic Types among Native Descendants in Argentina

Gastaldello

Iñiguez

Otsuki

et al. 2008

AIDS Research and Human Retroviruses

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“…This lineage is generally not as widespread among ancient highland groups (FehrenSchmitz et al, 2010b) and contemporary Andean populations (Fuselli et al, 2003;Lewis et al, 2005Lewis et al, , 2007AlvarezIglesias et al, 2007;Corella et al, 2007;Afonso Costa et al, 2010;Barbieri et al, 2011;Gaya-Vidal et al, 2011). The majority of the contemporary Andean populations are characterized by a high frequency of haplogroup B2 (Table S2), which is detected at a frequency of 25% in this RDP group from Humahuaca.…”

Section: Discussionmentioning

confidence: 99%

“…Population movements driven by the Incas in the region could be responsible, at least partially, for the dilution, or the loss, of some genetic lineages (Corella et al, 2007;Barbieri et al, 2011). This phenomenon was likely accentuated by the arrival of the European settlers (Hunley & Healy, 2011).…”

Section: Discussionmentioning

confidence: 99%

Genetic Diversity of a Late Prehispanic Group of the Quebrada de Humahuaca, Northwestern Argentina

Mendisco

Keyser

Seldes

et al. 2014

Annals of Human Genetics

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SummaryThis palaeogenetic study focused on the analysis of a late prehispanic Argentinean group from the Humahuaca valley, with the main aim of reconstructing its (micro)evolutionary history. The Humahuaca valley, a natural passageway from the eastern plains to the highlands, was the living environment of Andean societies whose cultural but especially biological diversity is still poorly understood. We analyzed the DNA extracted from 39 individuals who populated this upper valley during the Regional Development period (RDP) (between the 11th and 15th centuries CE), to determine their maternal and paternal genetic ancestry. Some mitochondrial and Y-chromosomal haplotypes specific to the Andean region are consistent with an origin in the highlands of Central Andes. On the other hand, a significant genetic affinity with contemporary admixed communities of the Chaco area was detected. Expectedly, recent demographic events, such as the expansion of the Inca Empire or the European colonization, have changed the original mitochondrial gene pool of the ancient Humahuaca Valley community. Finally, we identified a particular geographical organization of the prehispanic populations of Northwestern Argentina. Our results suggest that the communities of the region were divided between two different spheres of interaction, which is consistent with assumptions made by means of craniometric traits.

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“…The most common haplotype (B05) had a 16188–16189-16217 motif that was shared with another haplogroup B2 haplotype (B10). This motif was found among the Aymara and Quechua in the south central Andes in intermediate to high frequencies, suggesting a south central Andean origin for this haplotype (Álvarez-Iglesias et al, 2007; Barbieri et al, 2011; Corella et al, 2007; de Saint Pierre et al, 2012; Fuselli et al, 2003; Gayá-Vidal et al, 2011). This motif is also found in two of the Gran Chaco populations (the Pilaga, and Wichi) (Cabana et al, 2006).…”

Section: Resultsmentioning

confidence: 84%

“…Initial mitochondrial DNA (mtDNA) studies (Bert et al, 2001, 2004; Corella et al, 2007; Fuselli et al, 2003; Lewis et al, 2005, 2007b) included many Quechua speakers, but few Aymara speakers. Research focused mainly on the differences between Andean and Amazonian populations to contrast the micro-evolutionary processes that each region experienced and to test whether multiple migrations into South America could account for the differences.…”

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confidence: 99%

Mitochondrial variation among the aymara and the signatures of population expansion in the central Andes

Batai

Williams

2014

American J Hum Biol

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Objectives The exploitation of marine resources and intensive agriculture led to a marked population increase early in central Andean prehistory. Constant historic and prehistoric population movements also characterize this region. These features undoubtedly affected regional genetic variation, but the exact nature of these effects remains uncertain. Methods Mitochondrial DNA (mtDNA) hypervariable region I sequence variation in 61 Aymara individuals from La Paz, Bolivia, was analyzed and compared to sequences from 47 other South American populations to test hypotheses of whether increased female effective population size and gene flow influenced the mtDNA variation among central Andean populations. Results The Aymara and Quechua were genetically diverse showing evidence of population expansion and large effective population size, and a demographic expansion model fits the mtDNA variation found among central Andean populations well. Estimated migration rates and the results of AMOVA and multidimensional scaling analysis suggest that female gene flow was also an important factor, influencing genetic variation among the central Andeans as well as lowland populations from western South America. mtDNA variation in south central Andes correlated better with geographic proximity than with language, and fit a population continuity model. Conclusion The mtDNA data suggests that the central Andeans experienced population expansion, most likely because of rapid demographic expansion after introduction of intensive agriculture, but roles of female gene flow need to be further explored.

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Mitochondrial DNA diversity of the Amerindian populations living in the Andean Piedmont of Bolivia: Chimane, Moseten, Aymara and Quechua

Cited by 25 publications

References 34 publications

HTLV Type 1 Genetic Types among Native Descendants in Argentina

HTLV Type 1 Genetic Types among Native Descendants in Argentina

Genetic Diversity of a Late Prehispanic Group of the Quebrada de Humahuaca, Northwestern Argentina

Mitochondrial variation among the aymara and the signatures of population expansion in the central Andes

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