“…Its formation is associated with congenital, structural diseases of the connective tissues, including Marfan’s syndrome [8], mitral valve prolapse [15], LV outflow tract obstruction, hypertrophic cardiomyopathy [16, 17] and bicuspid or quadricuspid aortic valves [18, 19]. From these predisposing disorders, MVA is formed by acquired factors, such as rheumatic fever, Libman-Sachs endocarditis and, in most cases, infective endocarditis [2, 3, 20–22]. It is usually detected on the anterior leaflet, due to infective endocarditis caused by an aortic regurgitant jet striking the leaflet [9, 21, 22].…”