Mitral Annular Dimensions and Geometry in Patients With Functional Mitral Regurgitation and Mitral Valve Prolapse

Abstract

Moderate to severe MR was associated with increased MA dimensions, especially among patients with MVP compared with control subjects without cardiac disease. Moreover, unlike in controls and patients with MVP, annular enlargement in FMR was more closely associated with LA dilation.

Augmented resistive immersed surfaces valve model for the simulation of cardiac hemodynamics with isovolumetric phases

“…Immersed resistive valves, Σ 12 and Σ 23 , corresponding respectively to the mitral valve (see Figure 13C) and to the aortic valve (see Figure 13D) have been inserted into the geometry. The former has been designed with the software Materialise 3-Matic V11.0 ‡ from physiological in vivo data [29][30][31][32][33] whereas the latter is directly provided by Zygote 3D Human Heart Model. All ‡ https://www.materialise.com/fr/software/3-matic (last accessed 27 Feb 2019).…”

Preprocedural planning of transcatheter mitral valve interventions by multidetector CT: What the radiologist needs to know

“…The presence of leaflet calcification must also be reported, since severe calcifications along the device grasping zone are at higher risk of embolisation into the blood stream, and especially bulky calcifications of the anterior mitral valve leaflet could be displaced into the LVOT, resulting in LVOT obstruction [8,26,27]. …”

“…A posterior myocardial shelf is typically not recognisable in DMVD, and the basal myocardium may bulge into the lumen with hyperdynamic and hypertrophic left ventricle [12,24,25]. Of note, the myocardial shelf can change its morphology and size over the cardiac cycle and disappear in systole [26]. Therefore, the use of TMVR devices anchoring to the infero-lateral basal myocardium requires that the posterior myocardial shelf be identified and sized dynamically both in systole and diastole to ensure proper device capture and positioning [25,26].…”

“…Of note, the myocardial shelf can change its morphology and size over the cardiac cycle and disappear in systole [26]. Therefore, the use of TMVR devices anchoring to the infero-lateral basal myocardium requires that the posterior myocardial shelf be identified and sized dynamically both in systole and diastole to ensure proper device capture and positioning [25,26]. …”

“…the angle between the mitral annulus trajectory line and the LVOT long axis, which is directly related to the risk of TMVR-related LVOT obstruction) can be readily measured on 3-chamber MPR views (Fig. 12), and the neo-LVOT geometry after TMVR can be predicted on a patient- and device-specific basis by simulating device deployment via stereolithographic file integration [12,26,28]. Dedicated software plugins also allow prediction of the best fluoroscopic angulation for device placement based on preprocedural MDCT data [12,29].…”