Mitral leaflet separation to evaluate the severity of mitral stenosis: Validation of the index by transesophageal three‐dimensional echocardiography

Bigdelu, Leila; Poorzand, Hoorak; Azari, Ali; Jarahi, Lida; Ghaderi, Fereshteh; Fazlinejad, Afsoon; Alimi, Hedieh; Rohani, Atooshe; Manavifar, Negar

doi:10.1111/echo.13805

Cited by 9 publications

(8 citation statements)

References 23 publications

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“…On TEE, MSLI discriminatory ability between the different grades of MS was very good ( P < .001). There was a significant positive correlation between MLSI and 3D MVA ( r = .93, P < .001) 15 …”

Section: Discussionmentioning

confidence: 92%

Mitral leaflet separation index for mitral valve assessment during balloon mitral valvuloplasty

et al. 2020

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Objective The objective of the study was to evaluate the accuracy of the mitral leaflet separation index (MLSI) in selected patients with mitral stenosis, before and after percutaneous balloon mitral valvuloplasty (PBMV), compared to conventional methods with transthoracic echocardiography [TTE]. Methods A prospective study was conducted in 30 patients, ages 20‐60 years, with severe symptomatic mitral stenosis (MS) who had PBMV in the Cardiology Department, Zagazig University and National Heart Institute. A mean of three to five measurements of MLSI was taken in diastole in the parasternal long‐axis and apical four‐chamber views. The MLSI was re‐measured 24‐48 hours after PBMV. We calculated the correlation of the MLSI, pre and post BMV, with two‐dimensional (2D) MV planimetry and pressure half‐time (PHT) methods to assess MVA. Results There was a positive, highly significant correlation between pre PBMV 2D planimetry and MLSI (r = .665, P‐value < .001) as well as post PBMV 2D planimetry and MLSI (r = .410, P‐value = .025). A positive highly significant correlation was also noted between pre PBMV PHT and MLSI (r = .678, P‐value <.001) and between post PBMV PHT and MLSI (r = .706, P‐value <.001). Conclusion Mitral leaflet separation index is an easy and reliable measurement for the assessment of mitral stenosis before and after PBMV.

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Section: Discussionmentioning

confidence: 92%

Mitral leaflet separation index for mitral valve assessment during balloon mitral valvuloplasty

et al. 2020

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“…Two types of mechanical and biological valves are currently available for tricuspid valve replacement 10 . The isolated tricuspid valve surgery is routinely performed by cardiopulmonary bypass with (arrested heart) or without (beating heart) aortic cross‐clamp 11,12 . Surgeons have highly regarded the beating heart method due to its more protection against ischemia and reperfusion.…”

Section: Introductionmentioning

confidence: 99%

“…10 The isolated tricuspid valve surgery is routinely performed by cardiopulmonary bypass with (arrested heart) or without (beating heart) aortic cross-clamp. 11,12 Surgeons have highly regarded the beating heart method due to its more protection against ischemia and reperfusion. Although its advantages, the beating heart method has important disadvantages, including more incidence of thromboembolic events.…”

Section: Introductionmentioning

confidence: 99%

A comparative study on the results of beating and arrested heart isolated tricuspid valve surgery: A cross‐sectional study

Bigdelu

Azari

Mashayekhi

et al. 2022

Health Science Reports

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Background and Aims: The isolated tricuspid valve surgery is performed using beating or arrested heart surgery. The present study aimed to evaluate and compare the results of patients who underwent isolated tricuspid valve surgery using the beating and arrested heart techniques. Methods:In this retrospective observational study, all patients undergoing isolated tricuspid valve surgery between 2011 and 2018 were included. The patient's demographic information, echocardiographic, surgery, and hospitalization results were collected, and the EuroSCORE was calculated from the patient's medical records.Results: Fifty-three patients were included in the study of which 21 (39.63%) and 32 (60.37%) underwent a beating heart and arrested heart surgeries, respectively. There were no significant differences between the two studied groups in the echocardiographic results before and after the surgery, total hospitalization days (p = 0.56), and the mortality in the first 30 days after the surgery (p = 0.152). However, the duration of surgery (p < 0.001), EuroSCORE (p = 0.005), and patients who underwent lateral thoracotomy (p = 0.007) were notably lower in the arrested heart than in the beating heart group. In contrast, the duration of cardiopulmonary bypass and hospitalization in an intensive care unit after the surgery was remarkably lower in the beating heart than in the arrested heart group (p < 0.001 for both cases). Conclusion:Although there were some significant differences between the two kinds of surgery techniques, it seems superficial that made a particular decision to consider each method's superiority. Therefore, further studies with larger populations and meta-analyses are required to recommend the preferred method for the surgeons certainly.

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“…In contrast, chronic toxicity is irreversible and mostly happens within 1–3 months or even years after administering anthracycline 3 . Congestive heart failure is the most common type of anthracycline‐induced chronic cardiac toxicity, with a poor prognosis 4,5 . Therefore, early diagnosis of chemotherapy‐induced cardiotoxicity and left ventricular dysfunction is of high clinical importance 6 .…”

Section: Introductionmentioning

confidence: 99%

The effects of low‐dose anthracycline‐based chemotherapy on the levels of serum NT‐proBNP level and left ventricular systolic and diastolic dysfunctions: A prospective observational study

Mohammadi

Bigdelu

Allahyari

et al. 2022

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Background and Aims: The present study aimed to evaluate the relationship between serum N-terminal (NT)-pro-brain natriuretic peptide (BNP) levels and incidence of left ventricular (LV) systolic and diastolic dysfunction in patients who underwent low-dose anthracycline chemotherapy.Methods: This observational, prospective study was conducted on all patients with proven breast cancer, Hodgkin lymphoma, or non-Hodgkin lymphoma and no history of previous cardiac or any chronic diseases who were candidates for low-dose anthracycline chemotherapy from March 2017 to February 2018. We evaluated the serum NT-proBNP level and performed trans-thoracic echocardiography at baseline, 6, and 9 months after the chemotherapy.Results: Among 57 patients who successfully finished the study, 13 (22.8%) patients were men and 44 (77.19%) patients were women, and the total mean age was 52 ± 14.86 years. Our results revealed that the LV systolic and diastolic function and NT-proBNP mean levels were in the normal range at all three measured times.Additionally, no significant differences were observed between the levels of NT-proBNP, LV systolic, and diastolic function at baseline, 6, and 9 months after chemotherapy with low-dose anthracycline (p = 0.6, 0.1, and 0.4, respectively). Conclusion:Following low-dose anthracycline chemotherapy, none of our patients encountered LV systolic and diastolic dysfunctions and changes in serum NT-proBNP level. However, further studies with a larger population, longer follow-up duration, and higher dosage of anthracyclines are required to determine the effects of low-dose anthracycline on NT-proBNP level and LV systolic and diastolic functions.

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Mitral leaflet separation to evaluate the severity of mitral stenosis: Validation of the index by transesophageal three‐dimensional echocardiography

Abstract: MLSI showed an excellent ability to assess MS severity and correlates well with planimetered MVA measured by 3DTEE.

Cited by 9 publications

References 23 publications

Mitral leaflet separation index for mitral valve assessment during balloon mitral valvuloplasty

Mitral leaflet separation index for mitral valve assessment during balloon mitral valvuloplasty

A comparative study on the results of beating and arrested heart isolated tricuspid valve surgery: A cross‐sectional study

The effects of low‐dose anthracycline‐based chemotherapy on the levels of serum NT‐proBNP level and left ventricular systolic and diastolic dysfunctions: A prospective observational study

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