Mitral valve repair in patients with end stage cardiomyopathy: who benefits?

Gummert, Jan; Rahmel, Axel; Bucerius, Jan; Onnasch, Jörg-Friedrich; Doll, Nicolas; Walther, Thomas; Falk, Volkmar; Mohr, Friedrich W.

doi:10.1016/s1010-7940(03)00148-9

Cited by 80 publications

(45 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The mean LV ejection fraction was 23.9%, peak VO was 14, and LV end-diastolic dimension was nearly 70 mm. Remarkably, the operative mortality rate was only 1.6%, one of the lowest mortality rates of any series 8,10,12 and especially noteworthy because it represents the outcome of nearly 30 different centers. Twelve-month cumulative survival was 86.5%, and at 2 years, the cumulative survival was 85.2%.…”

mentioning

confidence: 92%

“…5,6 This view was challenged by Bolling and others Ͼ10 years ago. [7][8][9][10][11][12][13] The traditional hypothesis held that the mitral valve functions as a "pop off valve" for the failing ventricle and surgical correction results in a prohibitive mortality. The Bolling hypothesis is that there is "annular solution for ventricular problem…such that reconstruction of the mitral valve annulus geometric abnormality by an undersized ring, restores valvular competency, alleviates excessive ventricular workload, improves ventricular geometry, and improves ventricular function."…”

mentioning

confidence: 99%

See 1 more Smart Citation

Mitral Valve Repair in Patients With Advanced Heart Failure and Severe Functional Mitral Insufficiency Reverses Left Ventricular Remodeling and Improves Symptoms

Acker

2008

Circ: Heart Failure

View full text Add to dashboard Cite

mentioning

confidence: 92%

mentioning

confidence: 99%

Mitral Valve Repair in Patients With Advanced Heart Failure and Severe Functional Mitral Insufficiency Reverses Left Ventricular Remodeling and Improves Symptoms

Acker

2008

Circ: Heart Failure

View full text Add to dashboard Cite

“…6 Gummert and colleagues described a 30-day mortality rate of 6.1 % and a 5-year survival rate of 66 % in patients with dilated and ischaemic cardiomyopathy. 36 TV repair and atrial fibrillation ablation and atrial size reduction were the only accepted concomitant procedure. 6,36 Bax and colleagues reported their results for 51 patients undergoing coronary revascularisation and parallel restrictive MVRepair in ischaemic cardiomyopathy.…”

Section: Results Of Minimally Invasive Surgical Mitral Valve Repair Imentioning

confidence: 99%

Minimally Invasive Surgical Mitral Valve Repair: State of the Art Review

Praet

Stamm

Sündermann

et al. 2017

Interventional Cardiology Review

View full text Add to dashboard Cite

Minimally invasive surgical mitral valve repair (MVRepair) has become routine for the treatment of mitral valve regurgitation, and indications have been expanded to include reoperations. Current European Society of Cardiology/European Association for Cardio-Thoracic Surgery guidelines for the management of valvular heart disease recommended standards in terms of mitral valve disease differentiation, timing of intervention and surgical techniques to improve patient care. Numerous minimally invasive techniques to lessen the invasiveness have been described, such as the minimal-access J-sternotomy (ministernotomy), the parasternal incision, the port-access technique and the right minithoracotomy. Despite the development of catheter-based techniques, surgical repair remains the gold standard today for nearly all patients with degenerative valvular diseases and the majority of patients with other types of valvular diseases. Techniques include resection of the prolapsed segment, neo-chordae implantation and ring annuloplasty. In this review, the current indications for mitral valve surgery are summarised and state-of-the-art MVRepair techniques are highlighted.

show abstract

“…[11][12][13] However, the longer-term outcomes after the procedure are still largely unknown. [4][5][6][7]10 MVR is another option for cases of DCM with severe MR, [20][21][22] To a greater or lesser degree, MR coexists with severe DCM and the mechanism of MR is considered to involve tethering of the mitral leaflet by the papillary muscles, with dilatation of the mitral annulus. Mitral insufficiency leads to a vicious cycle of increasing volume overload of the dilated left ventricle, thus leading to progression of annular dilatation, worsening of MR and volume overload.…”

Section: Discussionmentioning

confidence: 99%

Outcome of Non-Transplant Surgical Strategy for End-Stage Dilated Cardiomyopathy in Young Children

Sugiyama

Hoshiai

Naitoh

et al. 2009

Circ J

View full text Add to dashboard Cite

Background:The shortage of heart transplantation donors is a problem, but partial left ventriculectomy (PLV) and mitral valve replacement (MVR) are feasible at the optimal timing, even in young children. Methods and Results: From May 1998 to May 2008, 11 children under the age of 3 years were diagnosed with severe dilated cardiomyopathy (DCM). Indications and outcomes of non-transplant surgical strategies were evaluated and 8 procedures were performed in 6 children: 5 PLV and 3 MVR. Two of them underwent MVR after PLV because of deterioration of mitral regurgitation (MR). Age at surgery ranged from 8 months to 2 years 11 months. Four are alive, of whom 1 eventually underwent a heart transplant overseas. Two children died during the study period: 1 who underwent only MVR died of intracranial bleeding during thrombolytic therapy for a thrombus stack valve and the other child died of congestive heart failure because of progressive MR 2 months after PLV. Follow-up after PLV ranged from 2 months to 8 years, and after MVR ranged from 1 month to 4 years. Conclusions: PLV and MVR are feasible and effective and should be considered when heart failure resists conventional therapy. (Circ J 2009; 73: 1045 -1048

show abstract

Mitral valve repair in patients with end stage cardiomyopathy: who benefits?

Abstract: MVR can be performed with low perioperative morbidity and mortality even in patients with advanced heart failure, modifying selection criteria for potential candidates may further improve long term outcome.

Cited by 80 publications

References 15 publications

Mitral Valve Repair in Patients With Advanced Heart Failure and Severe Functional Mitral Insufficiency Reverses Left Ventricular Remodeling and Improves Symptoms

Mitral Valve Repair in Patients With Advanced Heart Failure and Severe Functional Mitral Insufficiency Reverses Left Ventricular Remodeling and Improves Symptoms

Minimally Invasive Surgical Mitral Valve Repair: State of the Art Review

Outcome of Non-Transplant Surgical Strategy for End-Stage Dilated Cardiomyopathy in Young Children

Contact Info

Product

Resources

About