“…We have operated on 10 children with rheumatic activity at the time of surgery and all recovered without undue complications following valve replacement. [90][91][92][93][94][95][96][97][98][99][100][101][102][103][104][105][106][107][108] Furthermore, as the mechanical factor is important in children with terminal valvar disease, no child should be denied surgery however poor his condition. Low cardiac output and pulmonary edema are considered indications for emergency surgery.lOg Operation should be delayed for a few hours to permit intensive measures to improve the condition: Relief of hypoxia by endotracheal intubation and intermittent positive pressure respiration, improvement of cardiac output, renal flow and correction of acidosis by administration of dopamine, and stimulation of diuresis by large doses of intravenous furosemide.ll0…”