Mixed infection with COVID-19 and tropical malaria (case report)

Abstract

The article describes a clinical case of co-infection with COVID-19 and tropical malaria. Patient Z., 37 years old, arrived from the Central African Republic with a diagnosis of "New coronavirus infection COVID-19, confirmed (PCR RNA SARS-CoV-2 "+" from 27.01.22) mild form." During an objective examination, the subictericity of the sclera and skin integuments attracted attention, during thermometry - an increase in body temperature to 39.00C. Consciousness at the level of somnolence. Hemodynamics is unstable, episodes of arterial hypotension. Heart rate 96 per minute. Respiratory rate 24 in 1 minute, SpO2 95%, inspiratory dyspnea. According to a laboratory study, severe thrombocytopenia, pronounced signs of hepatic and renal insufficiency, hyperbilirubinemia, an increase in the concentration of C-reactive protein, procalcitonin were revealed. A differential diagnostic search was carried out between acute viral hepatitis and malaria. Blood microscopy revealed young trophozoites of Plasmodium falciparum (++++) using thick drop method. Antimalarial therapy was prescribed with Malacur, which was then replaced with parenteral Quinine followed by mefloquine. In parallel, extracorporeal detoxification operations were carried out. Against the background of adequate etiotropic therapy, complex intensive care measures, the patient's condition was stabilized, on the 40th day the patient was discharged from the hospital with the restoration of health.