Mixed ligand complex formation of 2-aminobenzamide with Cu(II) in the presence of some amino acids: Synthesis, structural, biological, pH-metric, spectrophotometric and thermodynamic studies

Dharmaraja, Jeyaprakash; Esakkidurai, Thirugnanasamy; Subbaraj, Paramasivam; Shobana, Sutha

doi:10.1016/j.saa.2013.05.043

Cited by 27 publications

(11 citation statements)

References 47 publications

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“…Mixed-ligand complexes have been extensively studied following recognition that they play an important role in biological processes and serve as suitable models for valuable information in the elucidation of enzymatic processes of biological relevance [7,8]. Also, these complexes showed significant antibacterial, antifungal, and anticancer activity [9][10][11][12][13][14][15].…”

Section: Introductionmentioning

confidence: 99%

Synthesis, spectral, X-ray diffraction, antimicrobial studies, and DNA binding properties of binary and ternary complexes of pentadentate N2O3 carbohydrazone ligands

Shebl

Khalil

2014

Monatsh Chem

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Two pentadentate carbohydrazone ligands, H 2 L 1 and H 2 L 2 , were prepared by the reaction of the bifunctional compound carbohydrazide with 2-hydroxy-5-nitrobenzaldehyde and 2-hydroxy-1-naphthaldehyde, respectively. Reactions of the ligands with oxovanadium(IV), cerium(III), thorium(IV), and dioxouranium(VI) ions yielded binary complexes. Reactions of the ligands with the dioxouranium(VI) ion in the presence of secondary ligands (8-hydroxyquinoline, glycine, salicylaldehyde, or benzoylacetone) yielded ternary complexes. The ligands and metal complexes were characterized by different techniques such as elemental and thermal analyses, IR, 1 H and 13 C NMR, electronic, ESR, mass spectra, and powder XRD as well as magnetic susceptibility and conductivity measurements. The coordinating sites are phenolic oxygen, azomethine nitrogen, and carbonyl oxygen. In complexes, the ligands act as dibasic pentadentate except ternary dioxouranium(VI) complexes, obtained using glycine or benzoylacetone, in which the ligands act as monobasic pentadentate. The XRD patterns for the H 2 L 1 ligand, its binary dioxouranium(VI) complex, and its 8-hydroxyquinoline ternary complex indicate crystalline nature and the grain size was estimated. The H 2 L 1 ligand and its binary complex have triclinic systems while the ternary complex has a monoclinic system with different unit-cell parameters. The ligands and some of their metal complexes showed antimicrobial activity toward some Gram-positive and Gram-negative bacteria, yeast (Candida albicans), and fungus (Aspergillus fumigatus), and MIC values were determined. The DNA binding properties of the oxovanadium(IV) complexes of H 2 L 1 and H 2 L 2 ligands were investigated by electronic absorption spectroscopy and viscosity measurements. The results indicated that these complexes bind to DNA via an intercalation binding mode with an intrinsic binding constant K b of 2.55 9 10 4 and 3 9 10 4 M -1 , respectively.

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Section: Introductionmentioning

confidence: 99%

Synthesis, spectral, X-ray diffraction, antimicrobial studies, and DNA binding properties of binary and ternary complexes of pentadentate N2O3 carbohydrazone ligands

Shebl

Khalil

2014

Monatsh Chem

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“…The synthesized ternary complexes inherited the main spectra from both Dhba and Nac. The v (OH) at 3449-3352 cm −1 and band at 834-806 cm −1 in all metal systems indicate the coordinated water molecule [6,19] . The bending of v (NH) at 758-745 cm −1 was still visible in the complexes, while the stretching of v (NH) at higher region cannot be observed since the band is probably stacked with the v (OH) band.…”

Section: Ternary Complexesmentioning

confidence: 90%

“…Several new bands can be found in the metal complex system. The first is the v (OH) band at 3478-3471 cm −1 and 837-811 cm −1 regions are due to coordinated water molecule [6,19] . Two new bands at 1618-1617 cm −1 and 1473-1431 cm −1 are contributed to v (COO − ) asy and v (COO − ) sym of deprotonated carboxylic group, v of 145-187 cm −1 suggests that this group is unbounded.…”

Section: Binary Complexesmentioning

confidence: 99%

“…Synthesis of chelate complex drugs is one of the solutions to deal with pathogenic microbes which are becoming more and more drug resistance [1,2] . Bioactive organic ligands such as amino acids, phenolic acids and alkaloids coupled with essential metals are frequently employed in chelate complex synthesis [3][4][5][6] . 2, 3-Dihydroxybenzoic acid (Dhba) is an effective phenolic compound not only with regard to its biological ability such as antioxidant, antibacterial and anti-inflammatory [7,8] , but also to its ability to form stable chelate complexes with various metal ions [9][10][11] .…”

Section: Introductionmentioning

confidence: 99%

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Synthesis, characterization, thermodynamics and biological studies of binary and ternary complexes including some divalent metal ions, 2, 3-dihydroxybenzoic acid and N -acetylcysteine

Santoso

Angkawijaya

et al. 2016

Journal of the Taiwan Institute of Chemical Engineers

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“…The dioxouranium (VI) complexes with N and O donor Schiff bases have been the subject of many investigations, moreover, in the last few decades, mixed ligand complexes have been extensively studied in solution as well as in the solid state and the ternary complexes are found to be more stable than binary complexes [5,6]. These mixed ligand complexes are used in a number of fields like biological, analytical, agricultural industrial and therapeutic applications [7]. Accordingly we intend to report herein, the synthesis and characterization of ternary complexes using Schiff base ligand with nitrogen, oxygen and sulphur donor sites [8] as primary ligand and 8hydroxyquinoline as coligand.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Characterization of Binary and Ternary Dioxouranium (VI) Complexes with Oxygen, Nitrogen and Sulphur Donor Ligands

Faheim¹

2014

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Mononuclear binary and ternary complexes of UO 2 2+ ion with N-salicylidene-4-Aminotoluene-3-sulfonic acid as primary ligand and 8-hydroxyquinoline as coligand have been prepared. The elemental analysis, molar conductance, IR and solid reflectance spectra in addition to the magnetic moment measurements, thermal study, XRD and SEM analysis were utilized to investigate the coordination behavior of these complexes. From the investigation data, all complexes have metal to ligand ratio of 1:1 and 1:1:1 with octahedral and dodecahedral geometry for binary and ternary complexes, respectively and the force constant, F U-O and bond length, R U-O were calculated. The thermal behavior of these complexes was investigated and the thermal decomposition pathways have been postulated showing that the final product is metal or metal oxide. Antimicrobial properties of the complexes have also been examined against Staphylococcus aureus (ATCC 25923), Streptococcus pyogenes (ATCC 19615), Pseudomonas fluorescens (S 97), Pseudomonas phaseolicola (GSPB 2828), Fusarium oxysporum and Aspergillus fumigatus. The corrosion inhibition of aluminum specimens in acidic solution was studied by weight loss method. The ternary complex, [UO 2 (HL)(8-Oqu)H 2 O] was found to be exhibits excellent inhibitory activity against the different microorganisms in addition to its corrosion inhibition efficiency towards Alspecimens in acidic solution more than the binary complex, [UO 2 (HL)NO 3 ].2H 2 O.

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Mixed ligand complex formation of 2-aminobenzamide with Cu(II) in the presence of some amino acids: Synthesis, structural, biological, pH-metric, spectrophotometric and thermodynamic studies

Cited by 27 publications

References 47 publications

Synthesis, spectral, X-ray diffraction, antimicrobial studies, and DNA binding properties of binary and ternary complexes of pentadentate N2O3 carbohydrazone ligands

Synthesis, spectral, X-ray diffraction, antimicrobial studies, and DNA binding properties of binary and ternary complexes of pentadentate N2O3 carbohydrazone ligands

Synthesis, characterization, thermodynamics and biological studies of binary and ternary complexes including some divalent metal ions, 2, 3-dihydroxybenzoic acid and N -acetylcysteine

Synthesis and Characterization of Binary and Ternary Dioxouranium (VI) Complexes with Oxygen, Nitrogen and Sulphur Donor Ligands

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