Mixed-Ligand Peroxo Complexes of Vanadium Containing 2-Thiouracil and its 6-methyl Derivative

Sarkar, Asit R.; Mandal, Shipra

doi:10.1080/00945710009351847

Cited by 14 publications

(5 citation statements)

References 25 publications

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“…The chemistry of transition metal complexes with mixed ligands is an area of current interest due to their structural diversity and usefulness. They have been reported to possess properties such as electrical conductivity [1], nonlinear optical applications [2], and antimicrobial activities [3,4]. Mixedligand complexes have a unique role in biological chemistry because they mimic biological molecules as millions of potential ligands are likely to compete for metal ions in vivo [5].…”

Section: Introductionmentioning

confidence: 99%

Synthesis, Biological, and Quantum Chemical Studies of Zn(II) and Ni(II) Mixed-Ligand Complexes Derived from N,N-Disubstituted Dithiocarbamate and Benzoic Acid

Ekennia¹,

Onwudiwe

Osowole

et al. 2016

Journal of Chemistry

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Some mixed-ligand complexes of Zn(II) and Ni(II) derived from the sodium salt ofN-alkyl-N-phenyl dithiocarbamate and benzoic acid have been prepared. The complexes are represented as ZnMDBz, ZnEDBz, NiMDBz, and NiEDBz (MD:N-methyl-N-phenyl dithiocarbamate, ED:N-ethyl-N-phenyl dithiocarbamate, and Bz: benzoate); and their coordination behavior was characterized on the basis of elemental analyses, IR, electronic spectra, magnetic and conductivity measurements, and quantum chemical calculations. The magnetic moment measurement and electronic spectra were in agreement with the four proposed coordinate geometries for nickel and zinc complexes and were corroborated by the theoretical quantum chemical calculations. The quantum chemically derived thermodynamics parameters revealed that the formation ofN-methyl-N-phenyl dithiocarbamate complexes is more thermodynamically favourable than that of theN-ethyl-N-phenyl dithiocarbamate complexes. The bioefficacy of the mixed-ligand complexes examined against different microbes showed moderate to high activity against the test microbes. The anti-inflammatory and antioxidant studies of the metal complexes showed that the ethyl substituted dithiocarbamate complexes exhibited better anti-inflammatory and antioxidant properties than the methyl substituted dithiocarbamate complexes.

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Section: Introductionmentioning

confidence: 99%

Synthesis, Biological, and Quantum Chemical Studies of Zn(II) and Ni(II) Mixed-Ligand Complexes Derived from N,N-Disubstituted Dithiocarbamate and Benzoic Acid

Ekennia¹,

Onwudiwe

Osowole

et al. 2016

Journal of Chemistry

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“…The details of the methodology for recording the various spectra, conductance, electrochemical studies and TGA were discussed earlier (Sarkar and Mandal, 2000). The details of the methodology for recording the various spectra, conductance, electrochemical studies and TGA were discussed earlier (Sarkar and Mandal, 2000).…”

Section: Methodsmentioning

confidence: 99%

“…Hence, to understand the functions of vanadium in different biological processes, it is necessary to develop its coordination chemistry with biologically relevant ligands such as peptides (Rehder, 1995). Hence, in continuation to our work on the interactions of vanadium with biologically important ligands (Sarkar and Mandal, 2000;Sarkar and Sarkar, 1997), we have undertaken the present work to explore the potential metal binding sites of L-carnosine (H 2 L) (Figure 1), which contains an imidazole moiety with respect to vanadium(IV and V). The metal complex of copper with L-carnosine as ligand in the solid state has been structurally characterized, where L-carnosine acts as a bridging dianionic ligand (Freeman and Szymanski, 1967) following the deprotonation of the amide and carboxyl proton.…”

Section: Introductionmentioning

confidence: 95%

A Model Study for Vanadium Protein Interactions: Synthesis, Characterization of Oxovanadium (IV and V) Complexes with L-carnosine

Sarkar¹,

Mandal²,

Pal³

et al. 2005

LSRT

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The potential metal binding sites of L-carnosine (b-alanyl-Lhistidine) with respect to vanadium has been investigated. Two novel oxovanadium complexes containing the dideprotonated Lcarnosine anion were isolated having the compositionThe dideprotonated L-carnosine coordinates to vanadium in both the complexes through the three donor atoms, namely the oxygen atom of the carboxylate group and two nitrogen (one each from the primary amine and the other from the amide group of the ligand). The imidazole moiety of L-carnosine undergoes a tautomeric change from N(3)-H to N(1)-H in the complex NH 4 [VO 2 L] . 2H 2 O. The nitrogen donor atom of the imidazole moiety coordinates to vanadium through N(3).

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“…The characteristic vibrational frequencies have been identified by comparing the spectra of the complexes with that of the parent ligand and literature value of absorption of simple type of compound (Table 1). The Schiff base exhibits a medium broad band at 3052 cm -1 , which may be due to the presence of intramolecular hydrogen bonding between phenolic hydrogen and azomethine nitrogen atom 17,18 . The absence of this band in the spectra of complexes indicates the deprotonation of the phenolic group and coordination of the oxygen atom to metal ion.…”

Section: Infrared Spectramentioning

confidence: 99%

Synthesis, Physiochemical, Thermal, Catalytic and Electrical Studies of Mn(III) VO(IV), MoO2(VI) and UO2(VI) Complexes with Unsymmetrical Schiff Base Ligand

2014

Chem Sci Trans

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The solid complexes of Mn(III), VO(IV), MoO 2 (VI) and UO 2 (VI) with unsymmetrical dibasic tetradentate ONNO donor Schiff base derived from the condensation of salicylaldenyde, o-hydroxy acetophenone and ethylene diamine have been synthesized and characterized by elemental analysis, magnetic susceptibility measurements, IR and reflectance spectra. The thermal dehydration and decomposition of these complexes were studied kinetically using the Horowitz-Metzger method. The solid state electrical conductivity of complexes has been measured in the temperature range 313 K≤ T ≥403 K and the complexes exhibited semiconducting behavior. Scanning electron micrograph has also been reported and suggested homogeneous phase material. Complexes were used for the catalytic oxidation of styrene.

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Mixed-Ligand Peroxo Complexes of Vanadium Containing 2-Thiouracil and its 6-methyl Derivative

Cited by 14 publications

References 25 publications

Synthesis, Biological, and Quantum Chemical Studies of Zn(II) and Ni(II) Mixed-Ligand Complexes Derived from N,N-Disubstituted Dithiocarbamate and Benzoic Acid

Synthesis, Biological, and Quantum Chemical Studies of Zn(II) and Ni(II) Mixed-Ligand Complexes Derived from N,N-Disubstituted Dithiocarbamate and Benzoic Acid

A Model Study for Vanadium Protein Interactions: Synthesis, Characterization of Oxovanadium (IV and V) Complexes with L-carnosine

Synthesis, Physiochemical, Thermal, Catalytic and Electrical Studies of Mn(III) VO(IV), MoO2(VI) and UO2(VI) Complexes with Unsymmetrical Schiff Base Ligand

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