Mixed mucinous cystadenoma with benign Brenner tumor in a huge ovarian mass, a case report and review of literature

Maghbool, Maryam; Samizadeh, Babak

doi:10.1016/j.ijscr.2022.106859

Cited by 4 publications

(5 citation statements)

References 9 publications

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“…It was also reported that about 20% of BTs could be accompanied by mucinous cystadenoma, serous cystadenoma, benign cystic teratoma, or struma ovarii (20). Similarly, in our study, seven patients (28%) had concomitant benign ovarian tumors: four cases were BBT combined with serous cystadenoma, seromucinous tumor, ovarian fibroma, and endometrioid cyst, respectively, and the other three were associated with mucinous cystadenoma, which was similar to what Roma and Masand reported (21,22). Some scholars believe that the reason why mucinous cystadenoma and BBT can coexist is that they have a common clonal origin (23,24).…”

Section: Discussionsupporting

confidence: 90%

Benign Brenner tumor of the ovary: two-dimensional and contrast-enhanced ultrasound features—a retrospective study from a single center

Chen,

Liao,

Cao

et al. 2024

Front. Oncol.

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ObjectiveBenign Brenner tumor (BBT) is a rare ovarian tumor, and there are few discrete reports about its manifestation in an ultrasound. This study sought to investigate the two-dimensional (2D) and contrast-enhanced ultrasound (CEUS) features of this entity.MethodsThis is a retrospective single-center study. The clinical manifestations, laboratory examination, and ultrasound data of 25 female patients with BBT were confirmed by pathology when they underwent 2D and/or CEUS examination at Ningbo First Hospital from January 2012 to June 2023. The ultrasound findings of the patients were analyzed using the terminology of the International Organization for the Analysis of Ovarian Tumor and were read by two senior sonographers who reached an agreement.ResultsAmong the all 25 patients, most of them were unilateral, and only one patient was bilateral. Thus, 26 lesions were found: 44.0% (11/25) were in the left and 52.0% (13/25) were in the right. Moreover, 53.84% (14/26) were solid lesions, 15.38% (4/26) were mixed lesions, and 26.92% (7/26) were cystic lesions. Among the solid-type patients, 42.85% (6/14) of the cases were with calcification. Upon laboratory examination, 12.0% (3/25) of the patients had high carbohydrate antigen 125 (CA-125) level, and 19.04% (4/21) of the patients had an elevated carbohydrate antigen724 (CA-724) level in the serum tumor markers. In the hormone test, 14.28% (3/21) were found to have a high postmenopausal estrogen level and 14.28%(3/21) were found to have a high level of follicle-stimulating hormone (FSH). One patient with complex manifestations and three with solid manifestations were examined by CEUS to observe the microcirculation perfusion of the tumor. One with solid and cystic separation was rapidly hyperenhanced and cleared, and the filling subsided faster than the uterus. The postoperative pathological diagnosis was benign Brenner tumor with mucinous cystadenoma. The other three cases were solid adnexal lesions, which showed isoenhancement on CEUS and disappeared slowly, synchronizing with the uterus. The CEUS results were considered as benign tumors and confirmed by pathology.ConclusionsBBT can show ovarian cystic, mixed cystic and solid type, and solid echo in 2D ultrasound. Unilateral ovarian fibrosis with punctate calcification is an important feature of BBT in 2D ultrasound. However, for solid adnexal masses and mixed cystic and solid masses with unclear diagnosis, if CEUS shows isoenhancement or hyperenhancement, the possibility of BBT cannot be excluded.

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Section: Discussionsupporting

confidence: 90%

Benign Brenner tumor of the ovary: two-dimensional and contrast-enhanced ultrasound features—a retrospective study from a single center

Chen,

Liao,

Cao

et al. 2024

Front. Oncol.

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“…In term of laterality Right:Left ovary ratio was found 4:3. [4,5,6,7,8,9,10] Our patient was also a post-menopausal woman with history of 5-month progressive abdominal discomfort and distention with huge 18 × 16 × 12 cm left ovarian mass who underwent explorative laprotomy with left adnexal excision and pathological diagnosis of borderline mucinous tumor associated with benign Brenner tumor was made. Ovarian mucinous tumors are divided into benign (mucinous cystadenoma), borderline, and malignant (mucinous carcinoma); majority mucinous tumors are benign or borderline.…”

Section: Discussionmentioning

confidence: 99%

“…[4] This is a case report of a 72-year-old female patient diagnosed with Brenner tumor that was discovered incidentally associated with a giant borderline mucinous tumor of the ovary. [5] Nazari F et al [6] Dougherty D et al [7] Rajshree D.K. et al [8] Pradhan P. et al [9] Anoedward et al [10] Sridevi S. et al [ On routine histological evaluation, final diagnosis stated mucinous cystic tumor of borderline malignancy with areas of benign mucinous cystadenoma along with benign Brenner tumor with transitional cell nests embedded in a dense fibrous stroma.…”

Section: Introductionmentioning

confidence: 99%

Borderline Mucinous Tumor with Benign Brenner Tumor in an Ovarian mass - A Case Report and Review of Literature

Bhandari,

Sharma,

Soni

2024

Int J Sci Healthcare Res

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Different groups of neoplastic and non-neoplastic conditions arise from the ovaries and the epithelial tumors such as Mucinous and Brenner tumors are rare neoplastic category. We present a case report of 72 year old postmenopausal woman who presented with progressively worsening abdominal discomfort and distention, diagnosed with huge Borderline Mucinous Tumor associated with Benign Brenner Tumor and also review the reported articles about this rare occurrence. Mucinous neoplasms of the ovary represent 10%–15% of ovarian neoplasms and about 80% of them are benign. Brenner tumors are a relatively rare epithelial neoplasm of the ovary that usually affect postmenopausal women and most of them are benign. Coexistence of Borderline Mucinous tumor with Benign Brenner tumor is a rare mixed epithelial tumor of the ovary. Keywords: Mucinous cystadenoma, Brenner tumor, Ovarian tumor

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“…În 30-36% din cazurile cu TOB, tumorile sincrone sunt detectate în ovarul ipsilateral sau contra-lateral, inclusiv chistadenom mucinos [1,7,12,13,17,18], chistadenom seros [7,13], endometriom [7], strumă ovariană [7], strumă ovariană și chistadenom mucinos [19], teratom ovarian matur [7], leiomiom ovarian [20], limfom [2]. În studiul Montoriol PF.…”

Section: Descrierea Cazului Clinicunclassified

“…Tratamentul de elecție pentru TOB este intervenția chirurgicală, al cărei volum este determinat de caracteristicile preoperatorii și intraoperatorii ale tumorii, de vârsta pacienților și de dorința de a păstra fertilitatea [1,7,15]. În cazul TOB benigne, la pacientele de vârstă reproductivă se efectuează intervenții tumor-/ovar-/anexectomie; în menopauză se efectuează histerectomie totală (HET) cu anexectomie bilaterală (AE) [1,7,12,13,18]. În TOB borderline, volumul intervențiilor chirurgicale la pacientele de vârstă fertilă este justificat de implementarea intervențiilor de conservare a organelor (AE) și a HET în combinație cu AE bilaterală la pacientele în menopauză și postmenopauză [11,13,15].…”

Section: Descrierea Cazului Clinicunclassified

Ovarian Brenner tumor

Mishina,

Gladun,

Sinitina

2024

BulMed

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Mixed mucinous cystadenoma with benign Brenner tumor in a huge ovarian mass, a case report and review of literature

Cited by 4 publications

References 9 publications

Benign Brenner tumor of the ovary: two-dimensional and contrast-enhanced ultrasound features—a retrospective study from a single center

Benign Brenner tumor of the ovary: two-dimensional and contrast-enhanced ultrasound features—a retrospective study from a single center

Borderline Mucinous Tumor with Benign Brenner Tumor in an Ovarian mass - A Case Report and Review of Literature

Ovarian Brenner tumor

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