Mixed venous oxygen saturation as a guide to tissue oxygenation and prognosis in patients with acute myocardial infarction

Clinical Significance of the Urinary Oxygen Tension in Patients with Ischemic Heart Disease

“…In contrast to dopamine, dobutamine does not have a renal vasodilator effect [21], Although the effect of a vasodilator on the RBF is controversial [22,23], a better relation between P11O2 and cardiac index in patients witli vasodilator and dobutamine indicates that the individual differences in the effect of vasodilator on RBF in our patients were not clinically significant. Mixed venous oxygen saturation has been demon strated to reflect peripheral tissue oxygen demand and uti lization and hence to predict the prognosis in patients with acute myocardial infarction [24], However, mixed venous oxygen saturation was not in relation to serum cre atinine or PuCF. Although the mixed venous oxygen satu ration is a good predictor of inadequate tissue oxygena tion [24], our data indicate that the PuCF is a better indi cator of RBF than mixed venous oxygen saturation.…”

“…Mixed venous oxygen saturation has been demon strated to reflect peripheral tissue oxygen demand and uti lization and hence to predict the prognosis in patients with acute myocardial infarction [24], However, mixed venous oxygen saturation was not in relation to serum cre atinine or PuCF. Although the mixed venous oxygen satu ration is a good predictor of inadequate tissue oxygena tion [24], our data indicate that the PuCF is a better indi cator of RBF than mixed venous oxygen saturation. Moreover, PuCF measurement is much easier and faster to perform than inulin, />aminohippuric acid, or creati nine clearance measurements in determining the RBF [25,26], There were no significant changes in mean blood pres sure, PaC>2 , and urine output from day 1 to day 2.…”

Interrelationship between oxygen‐related variables in patients with acute myocardial infarction: an interpretative review

“…Most of these studies were descriptive, and the majority of patients were prospectively and sequentially enroled (Table 1). The largest series from Sumimoto et al. (1991) studied 119 patients.…”

Oxygen Saturation Measurements in Acute Heart Failure Syndrome

“…The relation of mixed venous oxygen saturation, the cardiac index, tissue oxygenation, and prognosis has been investigated by Sumimoto et al (5) in 199 patients in the early phase of acute myocardial infarction. They found that a decreased mixed venous oxygen saturation in patients with acute myocardial infarction more reliably refl ected the presence of lactic acidosis and predicted a fatal outcome than did the simultaneously measured cardiac index.…”