Mixtures of antidepressant amphiphilic drug imipramine hydrochloride and anionic surfactant: Micellar and thermodynamic investigation

Khan, Farah; Rub, Malik Abdul; Azum, Naved; Asiri, Abdullah M.

doi:10.1002/poc.3812

Cited by 102 publications

(37 citation statements)

References 67 publications

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“…As a result, to attain approximately equal activity, it is repeatedly probable to blend a more surface‐active as well as costly surfactant with a somewhat fewer surface‐active as well as cheaper surfactant in various ratios. In the different applied field, the mixture of surfactants is used instead of single surfactant because of the better electrical and micellar properties of the mixed micelle as compared with the micelle of single surfactant . It is renowned that industrial surfactant systems are a mixture of dissimilar chemical varieties, for example, another surfactant or an amphiphile, electrolytes, dyes, or fillers.…”

Section: Introductionmentioning

confidence: 99%

Mixed micellization study of dodecyltrimethylammonium chloride and cetyltrimethylammonium bromide mixture in aqueous/urea medium at different temperatures: Theoretical and experimental view

Mahbub

Rub

Hoque

et al. 2018

J of Physical Organic Chem

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The behavior of mixed micelle formation between two cationic surfactants‐dodecyltrimethylammonium chloride (DTAC) and cetyltrimethylammonium bromide (CTAB) in absence/attendance of urea has been investigated by means of conductivity measurements over temperature range of 298.15 to 318.15 K. Lower magnitudes of the critical micelle concentration from their ideal values imply the strong interaction between the studied amphiphiles. The micellar mole fraction (X1) on the basis of the different proposed model (Rubingh, Motomura & Rodenas) and the ideal micellar mole fraction (Xid) were evaluated, and estimated results imply the high contribution of CTAB in the mixed micelle formation that enhances with the augment of the mole fraction of the CTAB. The values of activity coefficients (f1 and f2) (less than unity) and negative values of the interaction parameter (β) in all cases signify the attractive interaction between the amphiphiles studied. Spontaneous mixed micelle formation between the studied amphiphiles (dodecyltrimethylammonium chloride and CTAB) was indicated by the negative magnitudes of free energy of micellization (ΔGm0). The negative values of excess free energy of micellization (ΔGex) indicate the higher stability of the mixed micelle compared with the single micelle. The standard enthalpy change of micellization (ΔHm0) and standard entropy change of micellization (ΔSm0) were also calculated and discussed.

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Section: Introductionmentioning

confidence: 99%

Mixed micellization study of dodecyltrimethylammonium chloride and cetyltrimethylammonium bromide mixture in aqueous/urea medium at different temperatures: Theoretical and experimental view

Mahbub

Rub

Hoque

et al. 2018

J of Physical Organic Chem

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“…Rub et al found negative values of Δ H 0 c as well as Δ S 0 c for CP of some amphiphilic drugs in the participation of Tw 80 as well as in presence of other additives mixed system . But in case of micellization of amphiphilic drugs, both negative as well as positive values of enthalpy and entropy were found …”

Section: Resultsmentioning

confidence: 97%

Impact of different diols/polyols on the phase separation behavior as well as thermodynamic properties of tween 80

Mishu

Amin

Rub

et al. 2019

J of Physical Organic Chem

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Herein, the cloud points (CPs) of tween 80 (Tw 80) in water/(water + diols [ethanediol, propanediol, and butanediol])/(water + polyols [glucose, fructose, and sorbitol]) systems were measured. For diols‐Tw 80‐water system and polyols‐Tw 80‐water system, the CP values were obtained to reduce gradually with increasing content of diols and polyols at a particular concentration of Tw 80. For a certain concentration of Tw 80 having different contents of diols, the observed ∆H0c, as well as ∆S0c values, were negative over the range of concentration of diols studied, and the negative values of ∆H0c and ∆S0c were reduced with the enhancement of the content of diols. The values of ∆H0c were negative, which indicate the process was exothermic. The clouding process of Tw 80 in the presence of different diols is mainly enthalpy‐controlled process, while the contributions of enthalpy tend to reduce with enhancing of the contribution of diols. In the case of polyols‐Tw 80 mixture in an aqueous environment, the ∆Gc0 values were achieved positive. The values of ∆Hc0 and ∆Sco were obtained negative for studied systems, while the negative values reduce with enhancing of polyol (glucose and fructose) concentrations. For sorbitol‐Tw 80 system, the values of ∆Hc0 were observed to be negative and the negative magnitudes reduce with enhancing of sorbitol concentrations. The thermodynamic parameters of transfer are also evaluated and illustrated in detail.

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“…The obtained positive values of

normalΔ H_{c}^{0}

in water are due to disruption of the H 2 O structure in the hydrophobic portion of the amphiphilic molecules (Naqvi et al, ). On the other hand, the negative values of

normalΔ H_{c}^{0}

arise when hydration of water molecules around the polar group of the amphiphilic molecules becomes more significant as compared to the rupture of the H 2 O molecules around the hydrophobic portion (Hoque et al, ; Khan et al, ; Kumar et al, ; Kumar and Rub, ).…”

Section: Resultsmentioning

confidence: 99%

Effect of Various Electrolytes on the Phase Separation and Thermodynamic Properties of p‐Tert‐Alkylphenoxy Poly (Oxyethylene) Ether in the Absence/Presence of Drugs

Amin

Mahbub

Alam

et al. 2019

J Surfact & Detergents

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Cloud point (CP) measurements of 4‐(1,1,3,3‐tetramethylbutyl) phenyl‐polyethyleneglycol (Triton X‐100 (TX‐100)) were performed in aqueous solution in the presence of drug Amikacin sulfate (AS)/Neomycin sulfate (NS)/(AS/NS+ different inorganic salts). In aqueous solution, the CP values of TX‐100 first decrease with increasing concentration and then increase with increasing surfactant concentration. The CP values of TX‐100 solutions were found to increase with the increasing concentration of the AS/NS drug. The CP values of TX‐100‐AS/NS mixtures were also observed to decrease with the increase of the concentration of salt. Different thermodynamic parameters such as standard free energy (normalΔGc0), standard enthalpy (normalΔHc0) as well as the standard entropy (normalΔSc0) change of phase separation were calculated and discussed in relation to molecular interactions.

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Mixtures of antidepressant amphiphilic drug imipramine hydrochloride and anionic surfactant: Micellar and thermodynamic investigation

Cited by 102 publications

References 67 publications

Mixed micellization study of dodecyltrimethylammonium chloride and cetyltrimethylammonium bromide mixture in aqueous/urea medium at different temperatures: Theoretical and experimental view

Mixed micellization study of dodecyltrimethylammonium chloride and cetyltrimethylammonium bromide mixture in aqueous/urea medium at different temperatures: Theoretical and experimental view

Impact of different diols/polyols on the phase separation behavior as well as thermodynamic properties of tween 80

Effect of Various Electrolytes on the Phase Separation and Thermodynamic Properties of p‐Tert‐Alkylphenoxy Poly (Oxyethylene) Ether in the Absence/Presence of Drugs

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