Mixtures of diflubenzuron and p-chloroaniline changes the activities of enzymes biomarkers on tilapia fish (Oreochromis niloticus) in the presence and absence of soil

Dantzger, Darlene Denise; Jonsson, Cláudio Martín; Aoyama, Hiroshi

doi:10.1016/j.ecoenv.2017.10.054

Cited by 19 publications

(9 citation statements)

References 34 publications

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“…Rare minnow had longer latency to start moving at low concentrations of MS222; owing to the silent effect of the anesthetic, MS222 can also change myocardial activity by reducing the electrical excitability of the heart and can even cause cardiodepression, cardiac arrest, and respiratory arrest (Atlee and Bosnjak 1990; Martinez and Hedrick 2002). Although p ‐chloroaniline can induce methemoglobin formation (Chhabra et al 1990), splenic bladder, and liver tumors (Dantzger et al 2018), its toxicity is relatively low (Wu et al 2014); consequently it had little influence on the time spent from entering the tank to start moving at the beginning of the experiment. The increase in the frequency of boundary line crossing and decrease in the time spent from entering the tank to start moving indicated that test fish swam around frequently and anxiously owing to the discomfort caused by increasing chemical concentrations.…”

Section: Discussionmentioning

confidence: 99%

Chemicals Weaken Shoal Preference in the Rare Minnow Gobiocypris rarus

Qiu

Wang

et al. 2020

Environmental Toxicology and Chemistry

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Fish behavioral responses are sensitive to chemicals in the water. We tested rare minnow tested for their shoal preference, and the shoal (school) factors including nutritional status, body size, and shoal (school) size that can make their preference most stable were measured. Then shoal preference was measured again while fish and shoal were subjected to a concentration gradient of chemicals (cadmium ion [Cd 2+ ], tricaine methanesulfonate [MS222], and p-chloroaniline). The results showed that single rare minnow preferred shoals over blank control tanks. In addition, this preference was most stable when the shoal was well fed and contained 20 individuals 2 cm long. Although there was no significant response after exposure to p-chloroaniline, the time spent from entering the tank to start moving decreased greatly at concentrations of Cd 2+ >3 mg/L and MS222 >11 mg/L. The time the test fish spent close to the shoal significantly decreased at Cd 2+ >3 mg/L, MS222 >11 mg/L, and p-chloroaniline >10 mg/L, and the frequency of boundary line crossing increased at the same concentrations. The behavioral parameters changed by 20, 5, and 8 min once the lowest-observed-effect concentrations of Cd 2+ , MS222, and p-chloroaniline, respectively, were added. Our study provides useful information on rare minnow shoal preference that may be used for a biological early warning system.

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Section: Discussionmentioning

confidence: 99%

Chemicals Weaken Shoal Preference in the Rare Minnow Gobiocypris rarus

Qiu

Wang

et al. 2020

Environmental Toxicology and Chemistry

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“…So, a synergistic effect was observed with 75% PCA in the mixture, but an antagonistic effect was detected with the mixture containing 25% PCA. 5…”

Section: Diflubenzuron and P-chloroaniline/in Vivo Fish Toxicitymentioning

confidence: 99%

“…In tilapia (Oreochromis niloticus) fish the presence of soil contributed to diminish the PCA toxicity, either individually or in combination with DFB. 5 In the aquatic environment, the compounds can be differentially associated to soil particles diminishing their availability to the organisms. The presence of pollutants in aquatic systems can be considered a significant environmental problem.…”

Section: Effect Of the Soil/in Vivo Fish Toxicitymentioning

confidence: 99%

Effects of Pollutants and Role of the Soil in the Water Toxicity

Dantzger¹,

Aoyama²

2017

IJH

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“…These substances are also important for preventing insect-borne diseases [4][5][6]. Highly effective insecticides act on targets specific to nerves, muscles, liver structure, and oxidative stress [7][8][9][10][11][12][13]. The insecticide IGR (insect growth regulator), which is thought to have minimal effects on the environment and non-target organisms, has been used in the control of insects [14].…”

Section: Introductionmentioning

confidence: 99%

The Effects of Diflubenzuron on Acetylcholinesterase (EC 3.1.1.7) Activity and Liver Ultrastructure in Wistar Rats

Gül

Yiğit

YİĞİT

et al. 2023

Gazi University Journal of Science

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Diflubenzuron is a commonly used larvicide/biocidal substance. The present study aimed to reveal the effects of diflubenzuron on Acetylcholinesterase (AChE) enzymatic activity and liver histopathology of a mammalian species (rats). The animals fed with various doses of diflubenzuron and the liver tissues of rats were taken on the 10th, 20th, 25th, 45th days and sixth month. AChE activity of liver was measured by spectrophotometer. Tissues were embedded in Araldite 502 (Sigma), took ultrathin sections, and examined under a 100 CX II Transmission Electron Microscope. AChE activity in the chronic dose of diflubenzuron group was like that in the control group. The enzymatic activity in the subacute dose was found to be significantly different from the control group. After subacute dose exposure was terminated, the AChE activity was still lower on the 45th day compared with the control group. Chronic and subacute doses caused adverse effects to liver tissues, such as numerous mitochondria, abnormally structured nuclei in the hepatocytes and many lipid droplets in the sinusoids of the liver ultrastructure. After the subacute dose was terminated, liver damage was still observed on the 20th and 25th days, but the liver tissue was partly regenerated on the 45th day. Cellular damage might recover after 45 days, but AChE activity probably takes more time to reach a normal level.

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Mixtures of diflubenzuron and p-chloroaniline changes the activities of enzymes biomarkers on tilapia fish (Oreochromis niloticus) in the presence and absence of soil

Cited by 19 publications

References 34 publications

Chemicals Weaken Shoal Preference in the Rare Minnow Gobiocypris rarus

Chemicals Weaken Shoal Preference in the Rare Minnow Gobiocypris rarus

Effects of Pollutants and Role of the Soil in the Water Toxicity

The Effects of Diflubenzuron on Acetylcholinesterase (EC 3.1.1.7) Activity and Liver Ultrastructure in Wistar Rats

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