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Abstract

Distinct means have been developed to answer an increasing demand and need for methods that can accurately predict and detect the fertile phase of the menstrual cycle and fit various indications and changing situations of women's reproductive life. Methods based on the detection of direct fertility markers, such as hormonal tests and ultrasound, are more objective and accurate than traditional markers based on indirect markers, but cost and dependence on supplies limit their application. Nevertheless, these methods could be used during a few cycles either as support in the teaching phase or in difficult cases and for specific indications. Likewise, some new devices designed to facilitate recording and calculation of fertility signals could be combined with clinical methods to improve prediction and detection of the fertile phase. Besides the search for new fertility markers and the development of new methods, the possibility of combining already existing methods would certainly improve use-effectiveness and acceptance.

Salivary Proteome Profile of Women during Fertile Phase of Menstrual Cycle as Characterized by Mass Spectrometry

“…Most of the animals have limited and short fertile period, but the external indications and attractiveness synchronize with ovulation maximize the chance of successful fertilization. [ 8 9 ] In human, females do not show corresponding cyclical changes that would be an indicator of ovulation, therefore it was felt essential to develop a method to identify the time of ovulation during the reproductive cycle. [ 10 ] The time of ovulation in humans is associated with the fertile phase of menstrual cycle.…”