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Alekseev, I. E.; Antropov, A.E.

doi:10.1023/a:1020625027656

Cited by 1 publication

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“…Tin-113 having a radionuclidic purity .99.99% could be produced by the above method for IRG applications. 149 Cyclotron irradiation of Cd targets is an alternative procedure for preparing carrier-free 113 Sn. Irradiation of 111 Cd as a 25 mm thick foil target in a beam of 28 MeV a-particles produce 113 Sn.…”

Section: Possible Areas Of Applicationsmentioning

confidence: 99%

Industrial radionuclide generators: a potential step towards accelerating radiotracer investigations in industry

2013

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The novel use of industrial radionuclide generators (IRG) ensures onsite availability of short-lived radionuclides and is expected to contribute significantly to industrial radiotracer investigations. While IRG technology is in its infancy, the use of generator-derived radioisotopes is expected to have broad potential impact on industrial radiotracer investigations. The optimal combination of suitable IRGs and appropriate radiotracer agents will form the basis of such industrial radiotracer investigations. Development of IRGs customized for specific applications is currently under development and the utility of such systems is expected to pave the way for a variety of industry related applications in the areas of residence time distribution (RTD) study, flow rate measurement, leak detection, etc. In this review, we discuss the principles of radionuclide generators, assess major parent/daughter pairs of interest for IRG, and identify the expected utility of potentially useful IRGs. Availability of the parent radionuclides required for IRG fabrication is an important criterion and hence their production is also reviewed. This overview outlines a critical assessment of recent developments, the contemporary status, and key challenges and apertures to the near future. Increase in the knowledge and use of IRGs utilizing available resources will encourage expanded use of these systems for expected future industrial radiotracer studies.Prof. M. R. A.Pillai, PhD, DSc retired as Head, Radiopharmaceuticals Division, BARC in 2013. He worked at the University of Missouri-Columbia as postdoctoral research associate (1987-89) and as visiting professor (1994). He served the IAEA (2003IAEA ( -2010 as a Technical Officer, in which capacity he directed projects on isotopes and radiopharmaceuticals involving 40 countries as well published 14 IAEA documents. He is an Associate Editor of Cancer Biotherapy and Radiopharmaceuticals and is a member of the Editorial Boards of Current Medicinal Chemistry, Current Radiopharmaceuticals and the American Journal of Nuclear medicine and Molecular Imaging. He has authored three books, 130 papers including 10 review articles, and holds two US patents.

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Section: Possible Areas Of Applicationsmentioning

confidence: 99%