Liquid metals (LMs) are opening large spaces for achieving functional 3D printing. However, previous fabrication strategies ever developed so far can only address a specific printing task that has yet to fulfill various needs. Conceiving that all fabrications and their output quality are dominated by the interactions between printing inks and their ambient environment, this review is dedicated to presenting a generalized framework toward the ubiquitous LM 3D printing and summarizing its fabrication category thus integrated. A panoramic view is provided that intentionally administrating the interfacial interactions among different media can guide ink modification and printing optimization. Further, the interactions between LM inks and various media are interpreted, ranging from gases, and liquids to soft matters, biological tissues, and even rigid materials, exploring key mechanisms such as oxidation facilitation, heat dissipation, structural support, modulus matching, strong wettability, and high reactivity. Following that, the LM inks, typical printing technologies, diverse working media, and enabled applications are reviewed. The elucidation of these interactions, particularly physical and chemical effects, can lead to the incubation of future LM 3D printing centers. It is expected that interactional LM 3D printing can mold additive manufacturing into ever‐powerful tools in the coming time.