In this paper, we consider exact reflection symmetries with universal four-zero texture for quarks and leptons. The previous study of µ−τ reflection symmetries can be translated to forms P m * u,ν P = mu,ν, m * d,e = m d,e with P = diag (−1, 1, 1) in the basis of four-zero texture. We call such a symmetry reflection because it is just a extended CP symmetry and no longer a µ − τ reflection. These symmetries can constrain the Majorana phases and then enhance predictivity of the leptogenesis.In this scheme, fermion mass matrices are restricted to have only four parameters. It predicts the Dirac phase δCP ≃ 203 • and m1 ≃ 3 [meV] in the case of the normal hierarchy.Mass matrix of the right-handed neutrinos MR also exhibits a four-zero texture with the reflection symmetries because four-zero textures are type-I seesaw invariant. An u − ν unification predicts mass eigenvalues as (MR1 , MR2 , MR3) = (O(10 5 ) , O(10 9 ) , O(10 14 )) [GeV].