The K-shell ionization cross sections of Mn, Ni, Cu, Zn and Ge under 328 bombardment have been measured in the energy range from 5 to 48 MeV. The cross sections are compared with available theories based on a direct Coulomb ionization mechanism and with the predictions of the K-vacancy sharing process. This last process can reasonably account for the measured cross sections at high bombarding energies. The energy shifts of the K-and K~-lines and the KJK~-intensity ratios have also been measured. This information is used to deduce the defect configuration of the atoms. The mechanisms responsible for the multiple vacancy production are discussed.