MMP inhibition as a novel strategy for extracellular matrix preservation during whole liver decellularization

RETRACTED: 3D Printing of Alginate/Chitosan-Based Scaffold Empowered by Tyrosol-Loaded Niosome for Wound Healing Applications: In Vitro and In Vivo Performances

“…The primary function of MMPs is to remodel tissue via particular processes of proteolytic degradation . In normal conditions, MMPs are expressed at the basal level. , However, during the wound healing process, a broad range of growth factors and cytokines transcriptionally activate MMPs via various pathways …”

“…Several studies investigated the CS–AL-based scaffold’s effects on the healing process of skin wounds . A previous investigation exhibited the fact that AL wound dressings minimize bacterial infection at the wound site, maintain a physiologically moist microenvironment, and facilitate wound healing. − It has also been revealed that wounds treated with curcumin-loaded CS–AL scaffolds demonstrated a remarkably faster wound closure than that of the control groups . Moreover, another investigation showed that combining CS–AL with fucoidan significantly developed capillary formation and granulation tissue in wound areas on days 4, 9, and 14 .…”

“…37 In normal conditions, MMPs are expressed at the basal level. 90,91 However, during the wound healing process, a broad range of growth factors and cytokines transcriptionally activate MMPs via various pathways. 92 wound site.…”