Mn2+, Co2+, Cu2+ and Zn2+complexes with two macrocyclic ligands bearing l-lactate-like functions: potentiometric studies and evaluation of superoxide-scavenging properties of the Mn2+ complex

Delagrange, Samuel; Delgado, Rita; Nepveu, Françoise

doi:10.1016/s0162-0134(00)00090-8

Cited by 14 publications

(7 citation statements)

References 25 publications

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“…At micromolar concentrations, water molecules can act as competing ligands for copper(II), modifying the species distributions towards less coordinated species. To avoid this problem, when copper(II) complexes were prepared, a small excess of ligand was used in order to increase the complexation of the copper(II) ions [22]. As shown by the distributions curves the copper(II) complexes are completely formed at pH 7.4, except for L1 (see below).…”

Section: Synthesis Of the Macrocyclic Copper(ii) Complexesmentioning

confidence: 99%

Macrocyclic copper(II) complexes: Superoxide scavenging activity, structural studies and cytotoxicity evaluation

Fernandes

Gaspar

Cabral

et al. 2007

Journal of Inorganic Biochemistry

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Section: Synthesis Of the Macrocyclic Copper(ii) Complexesmentioning

confidence: 99%

Macrocyclic copper(II) complexes: Superoxide scavenging activity, structural studies and cytotoxicity evaluation

Fernandes

Gaspar

Cabral

et al. 2007

Journal of Inorganic Biochemistry

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“…1 H-13 C NMR spectra were obtained in DMSO-D 6 on JEOL NMR 400 MHz. Log was calculated by potentiometric methods as described in the literature [21].…”

Section: Methodsmentioning

confidence: 99%

Synthesis andIn VitroandIn VivoEvaluation of a New⁶⁸Ga-Semicarbazone Complex: Potential PET Radiopharmaceutical for Tumor Imaging

Alhokbany

Al‐Otaibi

Amer

et al. 2014

Journal of Chemistry

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In an attempt to develop new tumor imaging radiotracers with favorable biochemical properties, we have synthesized new68Ga-2-acetylpyridine semicarbazone (68Ga-[APSC]2) as a potential positron emission tomography (PET) tumor imaging agent using a straightforward and a one-step simple reaction. Radiochemical yield and purity were quantitative without HPLC purification. Biodistribution studies in nude mice model bearing human MDA-MB-231 cell line xenografts displayed significant tumor uptake of68Ga-[APSC]2radiotracer after 2 h postinjection (p.i.). The initial results demonstrate that68Ga-[APSC]2radiotracer may be useful probe for detecting and staging of hypoxic tumor using PET imaging modality.

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“…Manganese hyperfine splitting is not observed for either resonance. Manganese(II) complexes usually give [38][39][40] a sharp resonance at g ca. 2, and a six-line hyperfine splitting of this resonance is normally observed.…”

Section: Epr Spectramentioning

confidence: 99%

Synthesis, spectroscopy and redox properties of mononuclear manganese(II) and manganese(IV) complexes with N-(aryl)-pyridine-2-aldimine (L) and its amide derivatives. X-ray structural characterization of [Mn(MeL)2(NCS)2] (MeL = N-(4-methylphenyl)-pyridine-2-aldimine)

Lucas

Mitra

Biswas

et al. 2005

Transition Met Chem

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A series of mononuclear Mn II and Mn IV complexes of general formulae [MnL 2 (NCS) 2 ] (1a-1d) and [Mn(L¢) 2 (NCS) 2 ] (2a-2c) have been prepared where L are Schiff bases obtained by the condensation of pyridine-2-aldehyde with para-alkyl-substituted aniline, and L¢ are the corresponding amide ligands. The room temperature magnetic susceptibility data of (1a-1d) indicate that Mn II is in a high spin state. The cyclic voltammograms of (1a-1d) exhibit a one-electron quasi-reversible Mn II fiMn III oxidation. A linear correlation has been found when E 0 [Mn III /Mn II ] is plotted against Hammett r p parameters. X-ray crystallographic data of (1b) shows that the central Mn II ion adopts a distorted octahedral geometry with six different MnAN distances. Upon oxidation of Mn II complexes (1b-1d) by H 2 O 2 , the corresponding Mn IV complexes (2a-2c) were obtained, and the Schiff base ligands were oxidized to the corresponding amides. The lowest energy LMCT bands of these Mn IV complexes correlate linearly with Hammett r p parameters. The redox behavior of the Mn IV complexes has been investigated by cyclic voltammetry. E.p.r. spectra of the Mn II and Mn IV complexes are also reported.

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Mn2+, Co2+, Cu2+ and Zn2+complexes with two macrocyclic ligands bearing l-lactate-like functions: potentiometric studies and evaluation of superoxide-scavenging properties of the Mn2+ complex

Cited by 14 publications

References 25 publications

Macrocyclic copper(II) complexes: Superoxide scavenging activity, structural studies and cytotoxicity evaluation

Macrocyclic copper(II) complexes: Superoxide scavenging activity, structural studies and cytotoxicity evaluation

Synthesis andIn VitroandIn VivoEvaluation of a New⁶⁸Ga-Semicarbazone Complex: Potential PET Radiopharmaceutical for Tumor Imaging

Synthesis, spectroscopy and redox properties of mononuclear manganese(II) and manganese(IV) complexes with N-(aryl)-pyridine-2-aldimine (L) and its amide derivatives. X-ray structural characterization of [Mn(MeL)2(NCS)2] (MeL = N-(4-methylphenyl)-pyridine-2-aldimine)

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Mn2+, Co2+, Cu2+ and Zn2+complexes with two macrocyclic ligands bearing l-lactate-like functions: potentiometric studies and evaluation of superoxide-scavenging properties of the Mn2+ complex

Cited by 14 publications

References 25 publications

Macrocyclic copper(II) complexes: Superoxide scavenging activity, structural studies and cytotoxicity evaluation

Macrocyclic copper(II) complexes: Superoxide scavenging activity, structural studies and cytotoxicity evaluation

Synthesis andIn VitroandIn VivoEvaluation of a New68Ga-Semicarbazone Complex: Potential PET Radiopharmaceutical for Tumor Imaging

Synthesis, spectroscopy and redox properties of mononuclear manganese(II) and manganese(IV) complexes with N-(aryl)-pyridine-2-aldimine (L) and its amide derivatives. X-ray structural characterization of [Mn(MeL)2(NCS)2] (MeL = N-(4-methylphenyl)-pyridine-2-aldimine)

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Synthesis andIn VitroandIn VivoEvaluation of a New⁶⁸Ga-Semicarbazone Complex: Potential PET Radiopharmaceutical for Tumor Imaging