2022
DOI: 10.1093/ndt/gfac063.011
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MO059: Trajectory Analysis of the Kidney Organoid Proteome Extends its Modelling Potential of Disease

Abstract: BACKGROUND AND AIMS Kidney organoids are a valuable and innovative model to understand genetic diseases, kidney development and transcriptomic dynamics. However, their proteome has not been analyzed so far. It is unclear how their proteome changes during differentiation, and if more complex disease processes such as inflammatory tissue responses could be modelled with this approach. METHOD Here, we used proteomics to compare … Show more

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