Mo1494 EUS-Guided Radiofrequency Ablation (EUS-RFA) Using a Novel Internally Cooled Needle Electrode for Pancreatic Insulinoma: a Case Series in Humans

Lakhtakia, Sundeep; Ramchandani, Mohan; Gupta, Rajesh; Venugopal, Sushma; Galasso, Doménico; Reddy, Nageshwar

doi:10.1016/j.gie.2015.03.824

Cited by 6 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Six original articles published were considered appropriate to be included in the review article. All were human case series from India [ 12 ], UK [ 8 , 13 ], South Korea [ 10 ], and China [ 14 ] or a case report from Italy [ 11 ]. All studies have been summarized in Tables 1 and 2 .…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Endoscopic Ultrasound-Guided Radiofrequency Ablation of the Pancreatic Tumors: A Promising Tool in Management of Pancreatic Tumors

Changela

Patil²,

Duddempudi

et al. 2016

Canadian Journal of Gastroenterology and Hepatology

View full text Add to dashboard Cite

Objective. Radiofrequency ablation is a well-established antitumor treatment and is recognized as one of the least invasive therapeutic modalities for pancreatic neoplasm. Endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) delivery can be used to treat both pancreatic cancer and asymptomatic premalignant pancreatic neoplasms and may serve as a less invasive alternative to surgical resection. This is an appealing option that may result in less morbidity and mortality. The aim of this review was to summarize and evaluate the clinical and technical effectiveness of EUS-guided RFA of pancreatic neoplasms. Methods. A through literature review was performed to identify the studies describing this novel technique. In this review article, we have summarized human case series. The indications, techniques, limitations, and complications reported are discussed. Results. A total of six studies were included. Overall, a 100% technical success rate was reported in human studies. Complications related to endoscopic ultrasound-guided radiofrequency ablation delivery have been described; however, few cases have presented life-threatening outcomes. Conclusion. We believe that this novel technique can be a safe and effective alternative approach in the management of selected patients.

show abstract

Section: Resultsmentioning

confidence: 99%

“…In larger lesions, the Habib EUS-RFA probe and needle are pulled back as one unit and repositioned to ablate the lesion. This process can be repeated as many times as needed to ensure complete ablation of the lesion [ 12 – 14 ].…”

Section: Resultsmentioning

confidence: 99%

Endoscopic Ultrasound-Guided Radiofrequency Ablation of the Pancreatic Tumors: A Promising Tool in Management of Pancreatic Tumors

Changela

Patil²,

Duddempudi

et al. 2016

Canadian Journal of Gastroenterology and Hepatology

View full text Add to dashboard Cite

show abstract

“…323,324 EUS-RFA of pancreatic tumors has been performed for insulinomas, pancreatic ductal adenocarcinomas, renal cell carcinomas with pancreatic metastases, nonfunctional NETs, as well as intraductal papillary mucinous neoplasms (IPMNs). [325][326][327][328][329][330][331][332][333][334][335] The thermal energy delivered to the tumor may range from 60 to 100°C because temperatures exceeding 100°C increase the risk of adverse events, whereas the benefit derived from such high temperatures likely diminishes because of the immediate vaporization of periprobe tissue, leading to an increase in thermal impedance, which, in turn, can decrease the delivery of ablative energy. 336,337 The technical success rates in the current published case series range from 70% to 100%.…”

Section: Eus-guided Radiofrequency Ablationmentioning

confidence: 99%

Interventional gastroenterology in oncology

Wadhwa

Patel

Grover

et al. 2022

CA A Cancer J Clinicians

View full text Add to dashboard Cite

Cancer is one of the foremost health problems worldwide and is among the leading causes of death in the United States. Gastrointestinal tract cancers account for almost one third of the cancer‐related mortality globally, making it one of the deadliest groups of cancers. Early diagnosis and prompt management are key to preventing cancer‐related morbidity and mortality. With advancements in technology and endoscopic techniques, endoscopy has become the core in diagnosis and management of gastrointestinal tract cancers. In this extensive review, the authors discuss the role endoscopy plays in early detection, diagnosis, and management of esophageal, gastric, colorectal, pancreatic, ampullary, biliary tract, and small intestinal cancers.

show abstract

“…Lakhtakia et al . [ 33 ] reported rapid relief of symptoms and normalization of serum glucose, C-peptide levels, and fasting insulin up to 6 months in three patients treated with EUS-RFA.…”

Section: Endoscopic Ultrasound-guided Ablation Of Cystic and Solid Pamentioning

confidence: 99%

New developments in endoscopic ultrasound-guided therapies

Bhutani

Arora

2015

Endosc Ultrasound

View full text Add to dashboard Cite

Endoscopic ultrasound (EUS) has opened new horizons in minimally invasive therapies for diverse gastrointestinal pathologies. Digestive Disease Weak 2015 held in Washington, DC., USA featured exciting research articles on EUS-guided therapeutic procedures. EUS-guided biliary drainage has been attempted and described for many years. There seems to be a lot of interest among various international groups to compare this technique with other alternatives in terms of efficacy and safety. Similarly, EUS-guided pancreatic drainage of cysts and fluid collections continues to evolve with new stents and devices being developed specifically for deployment under endosonographic guidance. EUS-guided ablation of cystic pancreatic tumors is innovative but not always effective. Combining alcohol ablation with injecting chemotherapeutic agents may improve long-term results regarding efficacy. Similarly, for solid pancreatic tumors there appears to be ongoing interest and continuing efforts in injecting different chemotherapeutic or ablative agents, delivering fiducials for radiation guidance and even attempting ablation with radiofrequency. Gastric variceal treatment and EUS-guided anastomoses also continue to be investigated. This review article is focused on the recent developments in EUS-guided therapies presented at Digestive Disease Week (DDW) 2015.

show abstract

Mo1494 EUS-Guided Radiofrequency Ablation (EUS-RFA) Using a Novel Internally Cooled Needle Electrode for Pancreatic Insulinoma: a Case Series in Humans

Cited by 6 publications

References 0 publications

Endoscopic Ultrasound-Guided Radiofrequency Ablation of the Pancreatic Tumors: A Promising Tool in Management of Pancreatic Tumors

Endoscopic Ultrasound-Guided Radiofrequency Ablation of the Pancreatic Tumors: A Promising Tool in Management of Pancreatic Tumors

Interventional gastroenterology in oncology

New developments in endoscopic ultrasound-guided therapies

Contact Info

Product

Resources

About