Mo1662 Pentax I-SCAN™ With Electronic Magnification for the Real-Time Histological Prediction of Colonic Polyps: a Prospective Study Using a New Digital Chromoendoscopy Setting

Accuracy of i-Scan for Optical Diagnosis of Colonic Polyps: A Meta-Analysis

“…Of the 33 articles left for full text review, 23 articles were excluded as they were retrospective studies (n = 4), studies about detection rate of polyps (n = 6), studies without complete data(n = 2), or for other reasons(n = 11). Eventually, 10 full published [ 27 – 36 ] papers and 1 abstract [ 37 ] were selected according to the study inclusion criteria and exclusion criteria. 13 eligible studies were identified from the 11 articles.…”

“…13 eligible studies were identified from the 11 articles. For two articles, Carlos Robles-Medranda et al [ 37 ] and Sung Noh Hong et al [ 35 ], 2 eligible studies were identified from each of them. These studies from one article were performed with different i-Scan mode and met inclusion criteria.…”

“…The main characteristics of the included studies were listed in Table 1 . The 13 studies [ 27 – 37 ] included a total of 925 patients and 2312 polyps. 51.4% of all polyps were neoplastic verified by histology—the range was from 3.28% to 78.67%.…”

“…Three studies [ 29 , 32 , 36 ] were performed in Germany, three [ 33 , 35 ] in South Korea, two [ 37 ] in Ecuador, and each of Italy [ 31 ], Netherlands [ 34 ], Taiwan [ 28 ], UK [ 30 ], and USA [ 27 ] had one. In 11 studies [ 27 – 31 , 33 , 35 – 37 ] the endoscopic diagnosis of polyp was performed in real-time. However, two [ 32 , 34 ] were performed by reading static images which were collected from consecutively enrolled patients.…”

“…However, two [ 32 , 34 ] were performed by reading static images which were collected from consecutively enrolled patients. For the diagnostic criteria to predict polyp histology, Kudo pit pattern classification or modified Kudo pit pattern classification was used in six studies [ 27 – 29 , 32 , 35 ], Narrow Band Imaging International Colorectal Endoscopic (NICE) classification in three [ 31 , 37 ], and other criteria in four [ 30 , 33 , 34 , 36 ]. Six studies [ 27 – 28 , 30 , 33 – 34 , 36 ] analyzed the small polyps (≤ 10 mm in size).…”