Mo2074 Understanding the Etiologies, Clinical Spectrum and Diagnostic Challenge of Dumping Syndrome

Berg, Patrick; Hall, Mark A.; Sarosiek, Irene; McCallum, Richard W.

doi:10.1016/s0016-5085(13)62726-2

Cited by 4 publications

(3 citation statements)

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“…GIP also peaks at the same time. Increased insulin causes a reactive hypoglycemia, which can be \60 mg/dL, and the symptoms of late DS are explained by this reactive hypoglycemia [29]. During late DS, GLP-1 also inhibits glucagon, which further enhances hypoglycemia and can lead to fainting episodes.…”

Section: Hormone Maladaptationmentioning

confidence: 99%

“…Anticholinergics that may be used for these purposes include dicyclomine, hyoscyamine, and propantheline. Dosing of dicyclomine can range from 20 to 40 mg, three times a day, given 30 min before meals [29].…”

Section: Pharmacologic Treatmentmentioning

confidence: 99%

“…Conversion to a Roux-en-Y gastrojejunostomy may work in some cases, particularly after partial gastrectomy, as Roux limbs can be associated with abnormal motility that may even cause gastric stasis. Jejunal interposition (creating an anti-peristaltic limb between stomach and jejunum) is rarely used today, because research suggested that an anti-peristaltic limb caused excessive gastric retention requiring reversal [29].…”

Section: Surgical Treatmentmentioning

confidence: 99%

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Dumping Syndrome: A Review of the Current Concepts of Pathophysiology, Diagnosis, and Treatment

2015

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Gastric surgery has long been known to be a cause of dumping syndrome (DS). However, the increasing incidence of gastric bypass surgery, as well as reports of DS unrelated to previous gastric surgeries, has increased the importance of understanding DS in recent years. DS is due to the gastrointestinal response to voluminous and hyperosmolar chyme that is rapidly expelled from the stomach into the small intestine. This response involves neural and hormonal mechanisms. This review encompasses the symptoms, diagnosis, and treatment approaches of DS and also focuses on the current research status of the pathophysiology of DS.

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Section: Hormone Maladaptationmentioning

confidence: 99%

Section: Pharmacologic Treatmentmentioning

confidence: 99%

Section: Surgical Treatmentmentioning

confidence: 99%

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