Background
The ubiquity of mobile devices has made it possible for clinical decision‐support systems (CDSS) to become available to healthcare providers on handheld devices at the point‐of‐care, including in low‐ and middle‐income countries. The use of CDSS by providers can potentially improve adherence to treatment protocols and patient outcomes. However, the evidence on the effect of the use of CDSS on mobile devices needs to be synthesized. This review was carried out to support a World Health Organization (WHO) guideline that aimed to inform investments on the use of decision‐support tools on digital devices to strengthen primary healthcare.
Objectives
To assess the effects of digital clinical decision‐support systems (CDSS) accessible via mobile devices by primary healthcare providers in the context of primary care settings.
Search methods
We searched CENTRAL, MEDLINE, Embase, Global Index Medicus, POPLINE, and two trial registries from 1 January 2000 to 9 October 2020. We conducted a grey literature search using mHealthevidence.org and issued a call for papers through popular digital health communities of practice. Finally, we conducted citation searches of included studies.
Selection criteria
Study design: we included randomized trials, including full‐text studies, conference abstracts, and unpublished data irrespective of publication status or language of publication.
Types of participants: we included studies of all cadres of healthcare providers, including lay health workers and other individuals (administrative, managerial, and supervisory staff) involved in the delivery of primary healthcare services using clinical decision‐support tools; and studies of clients or patients receiving care from primary healthcare providers using digital decision‐support tools.
Types of interventions: we included studies comparing digital CDSS accessible via mobile devices with non‐digital CDSS or no intervention, in the context of primary care. CDSS could include clinical protocols, checklists, and other job‐aids which supported risk prioritization of patients. Mobile devices included mobile phones of any type (but not analogue landline telephones), as well as tablets, personal digital assistants, and smartphones. We excluded studies where digital CDSS were used on laptops or integrated with electronic medical records or other types of longitudinal tracking of clients.
Data collection and analysis
A machine learning classifier that gave each record a probability score of being a randomized trial screened all search results. Two review authors screened titles and abstracts of studies with more than 10% probability of being a randomized trial, and one review author screened those with less than 10% probability of being a randomized trial. We followed standard methodological procedures expected by Cochrane and the Effective Practice and Organisatio...