Mobile Health Applications and Medication Adherence of Patients With Hypertension: A Systematic Review and Meta-Analysis

Mikulski, Bruna Spiller; Bellei, Ericles Andrei; Biduski, Daiana; Marchi, Ana Carolina Bertoletti De

doi:10.1016/j.amepre.2021.11.003

Cited by 31 publications

(21 citation statements)

References 46 publications

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“…Self-efficacy refers to an individual's perception of his or her competence to successfully perform a behavior ( 37 ). Multiple studies have shown that patients with chronic diseases (such as hypertension, type 2 diabetes, and tuberculosis) with higher levels of self-efficacy tend to have higher treatment adherence ( 38 – 42 ). Parents with higher scores on the self-efficacy dimension have the higher subjective initiative in improving children's medication adherence, so their children's medication adherence scores are relatively higher, which suggests that improving parents' self-efficacy may be an effective way to improve children's medication adherence.…”

Section: Discussionmentioning

confidence: 99%

The Influence of Parents on Medication Adherence of Their Children in China: A Cross-Sectional Online Investigation Based on Health Belief Model

Liu

et al. 2022

Front. Public Health

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ObjectiveTo explore the influence of parents on the medication adherence of their children.Study DesignA cross-sectional online investigation.MethodsA questionnaire with 41 questions was designed based on the health belief model (HBM) distributed and collected online in 28 cities around China through multi-stage stratified sampling. The reliability of the questionnaire was assessed with Cronbach's α coefficient and split-half reliability, and its validity was evaluated with exploratory factor analysis and content validity index. The structural equation model (SEM) was constructed to explore the relationship between the parents' health beliefs and their children's medication adherence. Subgroup analysis was conducted to study the differences between parents with different demographic characteristics (male and female, rural and urban).Results573 questionnaires were included for analysis, with an effective rate of 62.97%. The Cronbach'α coefficient of the questionnaire was 0.821 > 0.6, the split-half reliability was 0.651 > 0.6, the I-CVI of each dimension were >0.78, and the S-CVI/AVE (I-CVI average) was 0.95 > 0.9. The result of the questionnaire exploratory factor analysis met the standard. According to the SEM, self-efficacy (λ = 0.177), perceived susceptibility (λ = −0.244), and perceived severity (λ = 0.243) were direct influencing factors of children's medication adherence. In the subgroup analysis, the model established by each subgroup was consistent with the model established by the overall sample. The absolute values of females' perceived susceptibility, severity, and self-efficacy for their children's medication adherence path coefficients were higher than males'.ConclusionParents' perceived severity and self-efficacy may positively impact on their children's medication adherence, while parents' susceptibility to children's medication non-adherence may negatively impact on children's medication adherence. Objective constraints, perceived barriers, and benefits may in directly impact on children's medication adherence. Women's health beliefs appear to have a more significant impact on their children's medication adherence than men's. It may be an effective strategy to increase their children's medication adherence by improving parents' health beliefs. Medical staff should explain medication adherence knowledge to the parents of children, and inform the children of the possible consequences of non-adherence with medication, to improve the subjective perception of parents on the severity of children's non-adherence with medication, and improve parents' self-efficacy in rational medication for children. In addition, attention should be paid to the mental health of the parents, and more social and psychological support.

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Section: Discussionmentioning

confidence: 99%

The Influence of Parents on Medication Adherence of Their Children in China: A Cross-Sectional Online Investigation Based on Health Belief Model

Liu

et al. 2022

Front. Public Health

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“…For subjects experiencing great benefit, continuing to adhere to their symptom-directed therapies may be challenging; modulator trials to date have been 'on top of' such drugs and impact could be lessened if they are dropped. Advances are being made in supporting patients with adherence in other areas, such as mobile health applications, smart inhalers and chipped pill containers 89,90 . Some people will experience side effects or tolerability issues.…”

Section: Responses To Treatments Including Cftr Modulators Varymentioning

confidence: 99%

Future therapies for cystic fibrosis

et al. 2023

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We are currently witnessing transformative change for people with cystic fibrosis with the introduction of small molecule, mutation-specific drugs capable of restoring function of the defective protein, cystic fibrosis transmembrane conductance regulator (CFTR). However, despite being a single gene disorder, there are multiple cystic fibrosis-causing genetic variants; mutation-specific drugs are not suitable for all genetic variants and also do not correct all the multisystem clinical manifestations of the disease. For many, there will remain a need for improved treatments. Those patients with gene variants responsive to CFTR modulators may have found these therapies to be transformational; research is now focusing on safely reducing the burden of symptom-directed treatment. However, modulators are not available in all parts of the globe, an issue which is further widening existing health inequalities. For patients who are not suitable for- or do not have access to- modulator drugs, alternative approaches are progressing through the trials pipeline. There will be challenges encountered in design and implementation of these trials, for which the established global CF infrastructure is a major advantage. Here, the Cystic Fibrosis National Research Strategy Group of the UK NIHR Respiratory Translational Research Collaboration looks to the future of cystic fibrosis therapies and consider priorities for future research and development.

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“…Study review [27] Mobile Health Applications and Medication Adherence of Patients with Hypertension.…”

Section: Applications In the Management Of Hypertensionmentioning

confidence: 99%

“…A review conducted to identify the role of mobile health applications on the management of hypertension indicated that improvements in blood pressure outcomes might be achieved through the use of smartphone applications that serve as medication reminders, offer patients with individualised feedback, and provide two-way communication with their healthcare professionals [26]. A study conducted to analyze the impacts of mobile health application on medical adherence of hypertension patients and the underlying factors showed that mobile health applications have a positive impact on medical adherence of hypertension patients and helps improve their conditions [27].…”

Section: Applications In the Management Of Hypertensionmentioning

confidence: 99%

Impact of Mobile Technology Solution on Self-Management in Patients with Hypertension: Advantages and Barriers

Alzahrani¹,

Gay²,

Alturki³

2022

IJACSA

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Hypertension is a major risk factor for cardiovascular morbidity and mortality. It is a condition that increases the high risk of heart, liver, and other diseases. Since hypertension is one of the biggest global public health issues, patients require more interventions to manage their blood pressure. The vast use of mobile phones and applications with medication features has turned a smartphone into a medical device. These tools are helpful for a physician in the treatment of hypertension. Mobile health applications are utilised to manage hypertension at the moment; however, there is a lack of information regarding their efficacy. Smartphones and their applications are evolving quickly hence the rise in the innovation of mobile health applications. Mobile-based applications are helpful in-patient education and reinforce the behaviour through constant reminders, medication, and appointment alarms. The main objective of this study is to determine the impact of mobile health applications on self-management in patients with hypertension and its advantages and disadvantages. We used publications from 2015 and later as a time frame and searched on the first five pages of Google Scholar, JSTOR, Hindawi, PubMed, and ResearchGate. We group all associated terms that might turn up articles on this subject in the search results. The total number of database records that we identified were 213, and the duplicate identified and removed were 117; hence the screened records were 96. The reports excluded based on abstract and title were 31. Articles with full text and have been accessed for final inclusion were 65. The excluded articles were 51, and the studies included in the qualitative analysis were 14.

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Mobile Health Applications and Medication Adherence of Patients With Hypertension: A Systematic Review and Meta-Analysis

Cited by 31 publications

References 46 publications

The Influence of Parents on Medication Adherence of Their Children in China: A Cross-Sectional Online Investigation Based on Health Belief Model

The Influence of Parents on Medication Adherence of Their Children in China: A Cross-Sectional Online Investigation Based on Health Belief Model

Future therapies for cystic fibrosis

Impact of Mobile Technology Solution on Self-Management in Patients with Hypertension: Advantages and Barriers

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