Modal-based, nonlinear Moving Horizon Estimation (MHE) and Model Predictive Control (MPC) strategies for very flexible aeroelastic systems are presented. They are underpinned by an aeroelastic model built from a 1D intrinsic (based on strains and velocities) description of geometrically-nonlinear beams and an unsteady Vortex Lattice aerodynamic model. Construction of a nonlinear, modal-based, reduced order model of the aeroelastic system, employing a state-space realisation of the linearised aerodynamics around an arbitrary reference point, allows us to capture the main nonlinear geometrical couplings at a very low computational cost.