Mode of delivery and maternal vitamin D deficiency: an optimized intelligent Bayesian network algorithm analysis of a stratified randomized controlled field trial

Amiri, Mina; Rostami, Maryam; Sheidaei, Ali; Fallahzadeh, Aida; Tehrani, Fahimeh Ramezani

doi:10.1038/s41598-023-35838-6

Cited by 4 publications

(1 citation statement)

References 51 publications

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“…Over the past decade, vitamin D has garnered increased attention due to its association with various deficiencies and health benefits. Numerous studies highlight the role of vitamin D in the development of pathologies during pregnancy, noting that maternal vitamin D status directly influences that of the newborn [ 1 , 2 , 3 , 4 ].…”

Section: Introductionmentioning

confidence: 99%

Consequences of Maternal Vitamin D Deficiency on Newborn Health

Dragomir,

Toader,

Gheoca Mutu

et al. 2024

Life

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Background and Objectives: Maternal–fetal gestational pathology is one of the biggest challenges in the field of health at this moment. The current study is designed to determine the effects of vitamin D on pregnancy, starting with the idea that impairment of vitamin D status is thought to be correlated with impairment of the newborn’s health. Materials and Methods: In this retrospective study, we tried to establish the link between vitamin D deficiency and maternal characteristics and also how it impacted the clinical status of the newborn. We analyzed a group of 260 patients: 130 pregnant women and 130 newborns, in whom vitamin D status was detected using the serum levels of 25-hydroxyvitamin D (25-(OH)D). Results: The results showed that vitamin D deficiency has a high incidence among pregnant women, as was presented in many important international studies. Our study also showed a positive, direct correlation between the mother’s and newborn’s vitamin D status. Conclusions: Taking into consideration that vitamin D deficiency has been correlated with many complications, both in maternal and newborn health, a serum level determination of 25-(OH)D is necessary in the first trimester of pregnancy, and after that, adequate supplementation is necessary in order to prevent any negative effects.

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Section: Introductionmentioning

confidence: 99%

Consequences of Maternal Vitamin D Deficiency on Newborn Health

Dragomir,

Toader,

Gheoca Mutu

et al. 2024

Life

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Predictive value of Vitamin D levels in pregnant women on gestational length and neonatal weight in China: a population-based retrospective study

Chen,

Chu,

Liu

et al. 2024

Reprod Biol Endocrinol

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Background Vitamin D deficiency, a common occurrence among pregnant women, is an emerging public health concern worldwide. According to research, prenatal vitamin D deficiency is associated with various complications. This study assessed the vitamin D status of pregnant women in Yanbian, Jilin Province, as well as the correlation and predictive value of their vitamin D levels in relation to gestational length (weeks) and fetal weight, aiming to provide a basis for clinical diagnosis and treatment. Methods We conducted a population-based retrospective study involving 510 pregnant women from August 2019 to October 2022. Blood samples were collected at 16–20 weeks of gestation for the detection of serum vitamin D levels. Statistical analyses were performed using SPSS 28.0 and R 4.1.0 software. Multifactorial logistic regression analysis was employed to establish whether each variable was a risk factor for deliveries at ≤ 38 gestational weeks and low fetal weight. These results were used to construct a risk prediction model, and the model’s predictive efficacy was evaluated. Results or differences with p < 0.05 were considered statistically significant. Results Multifactorial logistic regression analysis revealed that vitamin D ≤ 14.7 ng/mL(OR: 1.611; 95% CI: 1.120–2.318; P = 0.010), Bone Mineral Density (BMD) T-value ≤-1(OR: 1.540; 95%CI: 1.067–2.223; P = 0.021), and gestational hypertension(OR: 7.173; 95% CI: 1.482–34.724; P = 0.014) were the independent risk factors for deliveries at ≤ 38 gestational weeks. Additionally, vitamin D ≤ 14.7 ng/mL(OR: 1.610; 95%CI: 1.123–2.307; P = 0.009), BMD T-value ≤ -1(OR: 1.560; 95%CI: 1.085–2.243; P = 0.016), and gestational hypertension(OR: 4.262; 95% CI: 1.058–17.167; P = 0.041) were the independent risk factors for low fetal weight (< 3400 g). Conclusion This study revealed that low vitamin D levels are an independent risk factor for a short gestational length and low fetal weight. Prenatal low BMD T-value and comorbid hypertensive disorders were also found to increase the risk of a short gestational length and low fetal weight.

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The relationship between parity, mode of delivery, age at childbirth and bone mineral density: a cross-sectional study

ma,

Li,

et al. 2024

Preprint

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Background As a neuro-psycho-social event, birth can impact the maternal health. The relationship between birth and bone health remains unclear, requiring further research to explore their association. Methods Our study was based on data from the National Health and Nutrition Examination Survey (NHANES) (2005-2020). Propensity score matching, Welch's two-sample t-test, Linear mixed models and Partial correlation analysis were used to examine the relationship between birth and BMD. Results We obtained 5727 participants. Welch's two-sample t-test showed that delivered subjects had lower mean BMD of the lumbar spine and lower limbs. The data from the linear mixed model showed a decrease in BMD of lower limbs and a decrease in BMD of lower spine in delivered subjects compared to those who had not. The same analyses showed lower BMD. Partial correlation analysis showed a negative correlation between age at birth and BMD in women who gave birth vaginally. Conclusions Women who have given birth have lower BMD compared to women who have not given birth. At the same time, BMD is negatively correlated with parity and age at delivery. Most importantly, we found for the first time a damaging association between vaginal delivery and BMD of lower limbs.

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Mode of delivery and maternal vitamin D deficiency: an optimized intelligent Bayesian network algorithm analysis of a stratified randomized controlled field trial

Cited by 4 publications

References 51 publications

Consequences of Maternal Vitamin D Deficiency on Newborn Health

Consequences of Maternal Vitamin D Deficiency on Newborn Health

Predictive value of Vitamin D levels in pregnant women on gestational length and neonatal weight in China: a population-based retrospective study

The relationship between parity, mode of delivery, age at childbirth and bone mineral density: a cross-sectional study

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