The ASTM D6424 standard is used for general aviation piston engine knock detection and is tested for unleaded fuel candidates. Issues are discussed regarding the identification of knocking cycles, filtering frequency bands, and the effects of down-sampling for this knock detection technique. The knock tests were performed on the Continental TSIO-520-VB engine at 12,000 ft for take-off and cruise conditions using three different fuels, the standard leaded 100LL avgas and two unleaded fuel candidates. The ASTM D6424 knock detection method has its own particular disadvantages, which are detailed and compared to other knock detection methods including the third derivative of pressure signal and discrete wavelet transform. Updates to the standard include a minimum sampling rate of 0.2 CAD. Additionally, the current standard does not contain recommendations for filtering the cylinder pressure which results in over detection of knocking cycles with the two new aviation fuel candidates tested. Recommendations are provided regarding the pressure signal processing prior to ASTM D6424 knock-characterization.