2022
DOI: 10.1016/j.xjidi.2022.100110
|View full text |Cite
|
Sign up to set email alerts
|

Model-Based Meta-Analysis to Optimize Staphylococcus aureus‒Targeted Therapies for Atopic Dermatitis

Help me understand this report
View preprint versions

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1

Citation Types

0
3
0

Year Published

2023
2023
2024
2024

Publication Types

Select...
5
1

Relationship

0
6

Authors

Journals

citations
Cited by 7 publications
(3 citation statements)
references
References 96 publications
0
3
0
Order By: Relevance
“…S. aureus is a promising target for AD treatment because it induces both skin barrier damage and inflammation by producing various virulence factors (superantigen, proteases and other protein products) 13 . As AD pathogenesis involves dynamic interactions between S. aureus and coagulase‐negative Staphylococcus (CoNS), S. aureus ‐specific eradication without killing CoNS could be effective for patients with AD 115 . Anti‐staphylococcal interventions in AD are aimed at decreasing colonization by S. aureus and preventing the microbiome dysbiosis, thereby increasing the AMP of commensal bacteria.…”
Section: Anti‐staphylococcal Therapy In Adults and Children With Atop...mentioning
confidence: 99%
See 1 more Smart Citation
“…S. aureus is a promising target for AD treatment because it induces both skin barrier damage and inflammation by producing various virulence factors (superantigen, proteases and other protein products) 13 . As AD pathogenesis involves dynamic interactions between S. aureus and coagulase‐negative Staphylococcus (CoNS), S. aureus ‐specific eradication without killing CoNS could be effective for patients with AD 115 . Anti‐staphylococcal interventions in AD are aimed at decreasing colonization by S. aureus and preventing the microbiome dysbiosis, thereby increasing the AMP of commensal bacteria.…”
Section: Anti‐staphylococcal Therapy In Adults and Children With Atop...mentioning
confidence: 99%
“…13 As AD pathogenesis involves dynamic interactions between S. aureus and coagulase-negative Staphylococcus (CoNS), S. aureus-specific eradication without killing CoNS could be effective for patients with AD. 115 Anti-staphylococcal interventions in AD are aimed at decreasing colonization by S. aureus and preventing the microbiome dysbiosis, thereby increasing the AMP of commensal bacteria. Decreasing S. aureus colonization in AD patients should consequently decrease symptoms of AD and improve QoL.…”
Section: Innovative Approaches Specifically Targeting S Aureus Dysbio...mentioning
confidence: 99%
“…Staphylococci constitute a group of major commensal/pathogenic microorganisms of the human skin. Among them, Staphylococcus aureus (S. aureus) is a well-known coagulase-positive pathogen associated with many diseases, e.g., atopic dermatitis, bacteremia, and food poisoning [14][15][16][17][18] . S. aureus is rarely detected on healthy skin (an average of 1.1% of all skin bacteria), but becomes predominant (average: 65%) on the skin of patients with atopic dermatitis [19] .…”
Section: Introductionmentioning
confidence: 99%