Estimation of electric power load on electric power substation is an essential task for system operator in order to operate the system in a reliable and optimal manner. In this paper, machine learning with artificial neural network is used for forecasting the load at a particular hour of the day on an electric power substation. Historical load data at each hour of the day for the period from September-2018 to November-2018 is taken from 33/11 kV substation near Kakatiya University in Warangal. A new artificial neural network architecture is developed based on the approach used to forecast the load. The developed model is simulated in MATLAB with available historical data to forecast the load on 33/11 kV electric power substation. Based on the analysis it is observed that the proposed architecture forecasts the load with better accuracy.Keywords Artificial neural networks · Electric power load forecasting · Machine learning · Mean square error · Mean absolute percentage error List of symbols L(D, t) Load at Dth day and tth hour L(D, t − 1) Load at Dth day and (t − 1)th hour L(D, t − 2) Load at Dth day and (t − 2)th hour L(D, t − 3) Load at Dth day and (t − 3)th hour L(t, D − 1) Load at (D − 1)th day and tth hour L(t, D − 2) Load at (D − 2)th day and tth hour L(t, D − 3) Load at (D − 3)th day and tth hour L(t, D − 4) Load at (D − 4)th day and tth hour MAPE Mean absolute percentage error MSE Mean square error y Target i Actual output y Predicted i Predicted output m Number of samples R Regression coefficient * Venkataramana Veeramsetty,