Model for secondary nucleation in a suspension crystallizer

Meadhra, R.Ó.; Kramer, Herman J. M.; Rosmalen, G.M. van

doi:10.1002/aic.690420410

Cited by 35 publications

(21 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These values are well in the range of those reported for crystallization systems, between 0.5 and 2.5 [11]. The nucleation rate constants, k b , among the experiments match reasonably well especially considering that commonly the secondary nucleation is the major hurdle in developing scale-up rules in industrial crystallization [12]. The complex attrition phenomena that are expected to occur in an industrial crystallizer require a rigorous model to account for the crystal-crystal and crystal-crystallizer collisions which are influenced by the crystallizer geometry and hydrodynamics [13,14].…”

Section: The Empirical Kinetic Parameterssupporting

confidence: 78%

Crystallization kinetics of MgSO4·12H2O from different scales of batch cooling scraped crystallizers

Himawan¹,

Witkamp²

2006

Cryst. Res. Technol.

View full text Add to dashboard Cite

For reliably scaling up of crystallizers, a full kinetic model is required in addition to heat, mass and population balances. A method for extracting nucleation and growth kinetic parameters for scaling-up seeded batch cooling crystallization was developed and demonstrated with a 15 L and in a 115 L scraped crystallizer using MgSO 4 ⋅12H 2 O as the model system. The method includes fitting the time resolved measured solute concentration and the crystal size distributions with a dynamic population-based model. The kinetic parameters extracted from the bench-scale crystallizer agree with those obtained from the pilot scale, confirming that they can be employed for design purposes.

show abstract

Section: The Empirical Kinetic Parameterssupporting

confidence: 78%

Crystallization kinetics of MgSO4·12H2O from different scales of batch cooling scraped crystallizers

Himawan¹,

Witkamp²

2006

Cryst. Res. Technol.

View full text Add to dashboard Cite

show abstract

“…Sometimes the attrition size can be estimated from microscopic pictures of the interior of the attritted parent crystals submerged in a liquid with the same refractive index such that the crystal surface does not cloud the view on the crystal interior [48]. Sometimes the attrition size can be estimated from microscopic pictures of the interior of the attritted parent crystals submerged in a liquid with the same refractive index such that the crystal surface does not cloud the view on the crystal interior [48].…”

Section: Secondary Nucleationmentioning

confidence: 99%

Fundamentals of Industrial Crystallization

Horst

Schmidt

Ulrich

2015

Handbook of Crystal Growth

View full text Add to dashboard Cite

“…The dynamic trend of the median crystal size (L 50 ), that is depicted in Figure 3, was measured using the Malvern instrument. This trend can typically be observed during the start-up phase of such crystallizer types and is attributed to a combination of relative low rates of attrition/secondary nucleation and an efficient dissolution of small crystals [9,10]. The product samples were filtered on a Buchner filter using a blue band filter cloth and subsequently washed with pure ethanol.…”

Section: Solid Samplingmentioning

confidence: 99%

A Comparative Study of Various Size Distribution

Neumann

Kramer

2002

Part. Part. Syst. Charact.

View full text Add to dashboard Cite

One of the major product specifications of a crystalline material is the crystal size distribution (CSD). In order to monitor and control the CSD in an industrial crystallization process, on‐line sensors are required. Over the years, a number of techniques to measure the CSD have been established. In this paper, three instruments operated in an on‐line fashion and an off‐line method are compared. The instruments were the OPUS, a HELOS/VARIO (both manufactured by Sympatec) and a Malvern 2600c (manufactured by Malvern). They were implemented on an 1100‐l evaporative draft tube baffle (DTB) crystallizer producing ammonium sulfate crystals from aqueous solution. Samples from this crystallizer were also analyzed offline by wet sieving. The results show reasonably good agreement between the different on‐line techniques and the wet sieving technique concerning the shape of the distribution. However, there is a discrepancy regarding the absolute values, which can be explained by the fact that the techniques used are based on different measuring principles.

show abstract

Model for secondary nucleation in a suspension crystallizer

Cited by 35 publications

References 19 publications

Crystallization kinetics of MgSO4·12H2O from different scales of batch cooling scraped crystallizers

Crystallization kinetics of MgSO4·12H2O from different scales of batch cooling scraped crystallizers

Fundamentals of Industrial Crystallization

A Comparative Study of Various Size Distribution

Contact Info

Product

Resources

About