Abstract-This paper aims to establish a unified framework to handle both the exponential synchronization and state estimation problems for a class of nonlinear singularly perturbed complex networks (SPCNs). Each node in the SPCN comprises both "slow" and "fast" dynamics that reflects the singular perturbation behavior. General sector-like nonlinear function is employed to describe the nonlinearities existing in the network. All nodes in the SPCN have the same structures and properties. By utilizing a novel Lyapunov functional and the Kronecker product, it is shown that the addressed SPCN is synchronized if certain matrix inequalities are feasible. The state estimation problem is then studied for the same complex network, where the purpose is to design a state estimator to estimate the network states through available output measurements such that dynamics (both "slow" and "fast") of the estimation error is guaranteed to be globally asymptotically stable. Again, a matrix inequality approach is developed for the state estimation problem. Two numerical examples are presented to verify the effectiveness and merits of the proposed synchronization scheme and state estimation formulation. It is worth mentioning that our main results are still valid even if the "slow" subsystems within the network are unstable.