High-pile foundation is a common form of deep foundation commonly used in ocean environments, such as docks and bridge sites. Aiming at the problem of bearing capacity of high pile foundations, this paper proposes the calculation of bearing capacity and the analysis of scour depth of high pile foundations under the action of scour based on the modified p-y curve. In this paper, three kinds of scour mechanisms—natural evolution scour, general scour, and local scour—are described; and the calculation methods of scour widely used at present are compared and analyzed. The solution of the vertical stress of soil around the pile under local scour is solved and applied to the β method to solve the lateral resistance of the pile under local scour. The local erosion is equivalent to the whole erosion, and the expression of the ultimate soil resistance before and after the equivalent is calculated, respectively, according to the principle that the ultimate soil resistance at a certain point above the equivalent pile end remains unchanged. The distance from the equivalent soil surface to the pile end can be obtained simultaneously, and then the equivalent erosion depth, p-y curve of sand at different depths, and high pile bearing capacity can be obtained. Finally, it is found that the bending moment of a single pile body varies along the pile body in the form of a parabola, and the maximum bending moment of the pile body is below the mud surface and increases with the increase in horizontal load. When the scouring depth is 30 m, the horizontal load is 25 KN, and the maximum bending moment of the pile body is about 150 N·m. The data with a relative error greater than 10% accounted for only 16.6% of the total data, and the error between the calculated value and the measured value was small. The formula can predict the erosion depth more accurately.