Model to Predict Cause-Specific Mortality in Patients with Head and Neck Adenoid Cystic Carcinoma: A Competing Risk Analysis

Imanguli, Matin; Sumer, Baran D.

doi:10.1245/s10434-017-5862-y

Cited by 2 publications

(2 citation statements)

References 11 publications

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“…In our study, the outcome “cause-specific death” was identified used SEER cause-specific death classification. Some previous studies including breast cancer and prostate cancer also used SEER database to identify cause-specific death and performed competing risk analysis [ 25 , 26 ].…”

Section: Discussionmentioning

confidence: 99%

Association of age and cause-special mortality in patients with stage I/ II colon cancer: A population-based competing risk analysis

et al. 2020

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This study aimed to determine the probability and prognostic factors of colon cancer-specific mortality (CCSM) and noncancer-specific mortality (NCSM) for patients with stage I/II colon cancer and evaluate the association of age on cause-specific mortality. Materials and methods From Surveillance, Epidemiology, and End Results (SEER) database, we identified 33152 patients with stage I/II colon cancer undergoing surgery between 2004 and 2011. The cumulative incidence of CCSM and NCSM was calculated, and competing risk analysis was performed to investigate prognostic factors for cause-specific mortality. Results In patients <50, 50-75, and >75 years of age, 5-year cumulative incidence of CCSM was 5.7%, 7.8%, and 16.1%, respectively (overall, 10.6%); 5-year cumulative incidence of NCSM was 2.2%, 7.1%, and 26.9%, respectively (overall, 13.8%). The probability of CCSM and NCSM increased with advanced age. The 5-year cumulative incidence of CCSM was higher than NCSM in patients <50 years of age, whereas lower in patients >75 years of age. The probability of CCSM and NCSM was similar in patients 50-75 years of age. Competing-risk multivariable analysis demonstrated that increasing age was a strong predictor of CCSM (per year increase, SHR 1.03,95% confidence interval [CI]: 1.03-1.04). Age was most predictive of NCSM: (per year increase, SHR 1.08, 95% CI: 1.08-1.08). Conclusion Age was significantly associated with an increased cumulative incidence of CCSM and NCSM of patients with stage I/II colon cancer underwent surgery. NCSM was a significant competing event and should be adequately considered when performing survival analysis.

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Section: Discussionmentioning

confidence: 99%

Association of age and cause-special mortality in patients with stage I/ II colon cancer: A population-based competing risk analysis

et al. 2020

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“…The mostly indicated prognostic factors included pathological types, patient age, disease stage, surgical margin status, site of origin, perineural invasion, etc. (11,12).…”

Section: Introductionmentioning

confidence: 99%

Primary Adenoid Cystic Carcinoma of the Upper Anterior Mediastinum Mimicking a Thyroid Tumor: A Case Report and Review of Literature

Sun

et al. 2020

Front. Endocrinol.

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Primary adenoid cystic carcinoma (ACC) of the upper anterior mediastinum mimicking a thyroid tumor has rarely been seen in clinical practice and lacks a standard of care therapy. Here, we report a 47-year old female patient with an ACC originated from the upper anterior mediastinum presenting as a thyroid gland tumor. The patient received gross surgical resection of the tumor and underwent post-surgical chemotherapy and radiotherapy. The patient was free from local recurrence 3-years following initial treatment, but developed multiple lung metastases. She remains under clinical observation without discomfort and is still followed as an outpatient. Here, we also summarized recent reports of similar cases with hope to provide some experience for future clinical practice.

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Model to Predict Cause-Specific Mortality in Patients with Head and Neck Adenoid Cystic Carcinoma: A Competing Risk Analysis

Abstract: TXAdenoid cystic carcinoma is a relatively uncommon malignancy constituting approximately 1% of head and neck malignancies and approximately 10% of salivary gland tumors.

Cited by 2 publications

References 11 publications

Association of age and cause-special mortality in patients with stage I/ II colon cancer: A population-based competing risk analysis

Association of age and cause-special mortality in patients with stage I/ II colon cancer: A population-based competing risk analysis

Primary Adenoid Cystic Carcinoma of the Upper Anterior Mediastinum Mimicking a Thyroid Tumor: A Case Report and Review of Literature

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