“…To end the debate on whether or not climatic conditions can play an independent role-and, if so, to what extent-as a key modulating factor in COVID-19 onset and transmission [18,31,39], a number of other factors must be considered [24,40,41] in scenarios of not only high complexity, but also significant uncertainty, as mentioned at the beginning of this paper. The available number of cases and especially deaths in the total population are also influenced by the following factors: (i) the early detection of the pathogen; (ii) the number of investigations carried out, their statistical assessment, and possible under/overestimations [13,42,43]; (iii) demography in terms of population age and density [44,45]; (iv) urban texture, mobility, and social habits of the population [46,47]; (v) restrictions by local and national governments, such as quarantine and lockdown [35,48]; and (vi) medical care and susceptibility of the hosts [49][50][51]. These factors are almost entirely unrelated to h. On this topic, even in spite of possible correlations between some variables, the recent literature [52] has suggested that confounding factors, including some climatic ones [53][54][55][56][57], are nearly ready to be satisfactorily weighed.…”