Modeling and investigation on mixing characteristics of T &amp; Y-shaped micromixers for microfluidic devices

Kumar, Anil; Ganesh, D. Sai; Krishna, T. V.; Sashank, B.; Satyanarayana, T.

doi:10.1016/j.matpr.2021.11.474

Cited by 3 publications

(1 citation statement)

References 9 publications

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“…So far, researchers have mainly focused on studies of passive micromixers with T-type [ 16 , 17 , 18 , 19 , 20 , 21 ], Z-type [ 22 , 23 ] and Y-type [ 24 , 25 , 26 ] channel structures. They found that mixing in microchannels is mainly dependent on molecular diffusion and confirmed that passive micromixer optimization can improve mixing efficiency by creating a flow state for extruded or stretched fluid by placing an effective channel structure within the microchannel [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

Influence of Structural Parameters on the Performance of an Asymmetric Rhombus Micromixer with Baffles

Nai

Zhang

et al. 2023

Micromachines

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As an important part of lab−on−a−chip and micro−total analysis systems, micromixers have a wide range of applications in biochemical analysis, pharmaceutical preparation and material synthesis. In the work, a novel rhombic separation and recombination micromixer with baffles was presented to further improve the performance of the micromixer and study the effect of multiple structural parameters on mixing. The effects of the rhombic angle, the width ratio of sub−channel and the size and relative positions of baffles on the mixing index were studied numerically at different Reynolds numbers (Re), and the sensitivity of the mixing index to various structures was also investigated. The results showed that the mixing index increased with the subchannel’s width ratio and slowly decreased after reaching the peak value in the range of Re from 0.1 to 60. The maximum mixing index appeared when the width ratio was 6.5. The pressure drops in the microchannel were proportional to the width ratio. The mixing effect can be further improved by adding baffle structure to asymmetric rhombus micromixer, and more baffle quantity and larger baffle height were beneficial to the improvement of the mixing index. The research results can provide reference and new ideas for the structure design of passive micromixers.

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Section: Introductionmentioning

confidence: 99%

Influence of Structural Parameters on the Performance of an Asymmetric Rhombus Micromixer with Baffles

Nai

Zhang

et al. 2023

Micromachines

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Mixing Improvement in a T-Shaped Micro-Junction through Small Rectangular Cavities

et al. 2022

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The T-shaped micro-junction is among the most used geometry in microfluidic applications, and many design modifications of the channel walls have been proposed to enhance mixing. In this work, we investigate through numerical simulations the introduction of one pair of small rectangular cavities in the lateral walls of the mixing channel just downstream of the confluence region. The aim is to preserve the simple geometry that has contributed to spread the practical use of the T-shaped micro-junction while suggesting a modification that should, in principle, work jointly with the vortical structures present in the mixing channel, further enhancing their efficiency in mixing without significant additional pressure drops. The performance is analyzed in the different flow regimes occurring by increasing the Reynolds number. The cavities are effective in the two highly-mixed flow regimes, viz., the steady engulfment and the periodic asymmetric regimes. This presence does not interfere with the formation of the vortical structures that promote mixing by convection in these two regimes, but it further enhances the mixing of the inlet streams in the near-wall region of the mixing channel without any additional cost, leading to better performance than the classical configuration.

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Microfluidic Technology for Advanced Drug Delivery Systems

Patil

Nimdeo

2023

Advances in MEMS and Microfluidic Systems

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Drug delivery is a procedure to transport drugs to an appropriate site for effective action, achieving the benefits of drugs. In the past few decades, nano-sized drug particles have attracted many researchers to develop an efficient drug delivery system. Microfluidic technology, for its ability to synthesize precise nanoparticles with uniform size, has emerged as a reliable technology for drug delivery. The microreactor has been established as a promising device due to its ability to provide intensive mixing in low-dimension microchannels having a high surface-to-volume ratio. It synthesizes drug particles with higher encapsulation efficiency and uniform particle size. The enhancement in the encapsulation efficiency results in the controlled release of drug particles at the appropriate site for effective medication. In addition, other applications of microreactors to synthesize various organic and inorganic nanoparticles are also discussed in this chapter.

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Modeling and investigation on mixing characteristics of T & Y-shaped micromixers for microfluidic devices

Cited by 3 publications

References 9 publications

Influence of Structural Parameters on the Performance of an Asymmetric Rhombus Micromixer with Baffles

Influence of Structural Parameters on the Performance of an Asymmetric Rhombus Micromixer with Baffles

Mixing Improvement in a T-Shaped Micro-Junction through Small Rectangular Cavities

Microfluidic Technology for Advanced Drug Delivery Systems

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