The development of any modern communication system is impossible without an accurate understanding of the channel that is supposed to be used to transmit information. At the same time, at the stage of theoretical research it is necessary to use mathematical models of channels, the adequacy of which to the real processes occurring in radio links largely determines the validity of the technical decisions made. This article is devoted to modeling modern MIMO systems in channels with various fading conditions. For this purpose, mathematical models of continuous communication channels, represented in the form of stochastic differential and difference equations, in radio relay and tropospheric communication lines were obtained and analyzed.