Blue-green infrastructure (BGI) has been recognized as an important tool for sustainable urban stormwater management. BGI is ecosystem-based, relying on biophysical processes, such as detention, storage, infiltration, and biological uptake of pollutants, to manage stormwater quantity and quality. Rain gardens, bioswales, constructed wetlands, retention and detention basins, and green roofs are most commonly used BGI systems. Unlike the single-functioned grey infrastructure, which is the conventional urban drainage system, these landscape systems collectively provide multiple ecosystem services, including flood risk mitigation, water quality treatment, thermal reduction, and urban biodiversity enhancement. In recent years, BGI is increasingly embraced through different initiatives around the world, driven by the urgency to tackle different local challenges, such as water quality standards, water security, increased flood risk, and aquatic ecosystem degradation. Whereas BGI is a relatively new term, the idea and practice are not new. In this chapter, we also showcase four cities-Portland, New York City, Singapore, and Zhenjiang-that are active and progressive in implementing BGI. Although BGI receives increasing attention, mainstreaming BGI remains a challenge today. To promote widespread BGI implementation, future research should focus on case studies on practical BGI experiences to inform strategies for overcoming the barriers to mainstreaming BGI in different cities.