An efficient and effective portfolio provides maximum return potential with minimum risk by choosing an optimal balance among assets. Therefore, the objective of this study is to analyze the performance of optimized portfolios in minimizing risk and achieving maximum returns in the dynamics of Timor-Leste’s equity portfolio in the international capital market for the period from January 2006 to December 2019. The empirical findings of this study indicate that the correlation matrix showed that JPM has a very strong positive correlation with one of the twenty assets, namely BAC (0.80). Moreover, the optimal portfolio of the twenty stocks exceeding 10% consists of four consecutive stocks, namely DGE.L (10.69%), NSRGY (10.37%), JPM (10.04%), and T (10.03%). In addition, the minimum portfolio consists of two stocks with a minimum variance of more than 10%, namely SAP.DE (11.20%) and DGE.L (10.39%). The evaluation of the optimal portfolio using Markowitz parameters also showed that the highest expected return and the lowest risk were 1.22% and 3.12%, respectively.