2021
DOI: 10.1016/j.bpj.2020.11.523
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Modeling Membrane Dynamics in 3D using Discrete Differential Geometry

Abstract: Biomembranes adopt varying morphological configurations that are vital to cellular functions. Many studies use computational modeling to understand how various mechanochemical factors contribute to membrane shape transformations. Compared to traditional approximation-based methods (e.g., finite element method), the class of discrete mesh models offers greater flexibility to simulate complex physics and shapes in three dimensions; its formulation produces an efficient algorithm while maintaining expressive coor… Show more

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