We demonstrate through a simple model validated by molecular dynamicsbased simulations that terahertz-speed, many-valued logic computations, and digital signal processing, functional for several cycles of operations are potentially possible with electric field-effect, dipole-dipole coupled protein architectures with various dipole moment orientations. Many-valued logic can be applied in various areas, such as artificial intelligence, machine learning, and robotics. Furthermore, programmable logic arrays and field programmable gate arrays can also benefit from its implementation. Even top companies like Intel developed circuits based on such logic (eg, StrataFlash and a NOR flash memory). The present study suggests that multivalued logic states can be stored in a protein with the application of proper external electric fields, and digital signal propagation is potentially achievable using dipole-dipole coupled molecules, placed few nanometers (on the order of 10 nm) apart. Furthermore, we propose a Dronpa protein-based ternary logic gate, suitable for universal ternary logic computations. The architectures are potentially operational at room temperature. The proposed operational principle is not restricted to proteins only; it might be applied in case of other types of molecules or artificial structures exhibiting similar behavior.