2014
DOI: 10.1142/s0218213014500109
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Modeling of Parkinson's Disease Using Fuzzy Cognitive Maps and Non-Linear Hebbian Learning

Abstract: Parkinson's disease is a chronic, progressive, age-related, neurodegenerative disorder that affects a large population around the world. A mathematical model for Parkinson's disease is presented using Fuzzy Cognitive Maps (FCMs). Basic theories of FCMs are reviewed and presented. Decision Support Systems (DSS) for medical problems are reviewed. Non-linear Hebbian learning techniques are considered in studying Medical problems and a generic algorithm is presented. The proposed method used the knowledge of a num… Show more

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Cited by 17 publications
(16 citation statements)
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“…where € is the tolerance level minimising the changes in the DOC values. When the conditions for termination of the algorithm are met, the final weight matrix, W NHL , is obtained [13,15]. Algorithm flowchart is shown in Fig.…”
Section: Nhl Algorithmmentioning
confidence: 99%
“…where € is the tolerance level minimising the changes in the DOC values. When the conditions for termination of the algorithm are met, the final weight matrix, W NHL , is obtained [13,15]. Algorithm flowchart is shown in Fig.…”
Section: Nhl Algorithmmentioning
confidence: 99%
“…These models involve updating the node state values and the causal relationships between concepts to simulate dynamic behavior. A number of weight-learning methods, such as Hebbian learning [26,27], genetic algorithm (GA) [28], and swarm intelligence optimization algorithm [29], have been applied to learning weights of an FCM. However, most of these methods require domain experts who can specify in advance the initial weight matrix of an FCM.…”
Section: Fuzzy Cognitive Mapmentioning
confidence: 99%
“…Most learning algorithms [26,27] for FCMs require domain experts who can predetermine the initial weight matrix. Moreover, GA [28] and swarm intelligence optimization algorithms [29] present low running speeds and induce network instability.…”
Section: Proposed Learning Algorithm For Fcmsmentioning
confidence: 99%
“…There have been many studies in medicine over the past years using the fuzzy cognitive map and nonlinear Hebbian learning algorithm method. These studies have included the classification of the autism disorder [9], modelling the Parkinson's disease [10], classification of breast lesions [5,11], and Grading celiac disease [12]. In a previous study [9], the onset of childhood autism was predicted with regard to 23 major factors of the disease, such as enjoy being swung, take an interest in other children, and climbing on things.…”
Section: Introductionmentioning
confidence: 99%
“…Finally, the disease was classified into 3 categories (definite autism, no autism, probable autism), and the system accuracy was reported by 79.9%. In another study [10], Parkinson mathematical modelling was provided based on 6 main factors of the disease, such as tremor, rigidity, and posture. Then, the disease was classified into 6 stages (healthy, stage 1, stage 2, stage 3, stage 4, stage 5 and stage 6), the obtained results were compared and simulated with and without the use of NHL algorithm.…”
Section: Introductionmentioning
confidence: 99%