The aim of this study is to investigate the corrosion behavior of anodized Zr in oral cavity environment simulated by Afnor saliva as a function of the amount of dissolved oxygen. For comparison, non treated Zr was also investigated in the same conditions. In order to study the corrosion behavior at open circuit potential versus time, cyclic potentiodynamic polarization (CPP) and electrochemical impedance spectroscopy (EIS) were performed. scanning electron microscopy (SEM) with energy dispersive X‐ray (EDX) imaging was used to observe the morphology and topography of the modified electrodes. Experimental data show that the decrease of oxygen concentration leads to the inhibition of the corrosion process for non treated Zr and Zr covered with nanotubes. A range of electrochemical stability of zirconia nanotubes in artificial Afnor saliva as a function of oxygen content in simulated oral cavity environment was established.