Modeling Schemes for Control of Bed-Temperature Gradients in Solid-State Fermentation

Abstract

Mathematical modeling is a useful tool to represent true processes on solid-state fermentation, more employed on scale-up and for better automatic control strategy designs. In the case of temperature profiles during the growth of microorganisms, models reproduce the events well, given valuable information to prevent or know the maximum temperature along the process. The election of differential mathematical models over others are better to use because of the simplicity and further modifications on the models, according to different bioreactor design, they could improve solid fermentation processes. In the present work, a review on the mathematical models for heat transfer in packed bed bioreactor is showed. In order to evaluate the best models for control design effects, the main characteristics for the models reported in the literature are discussed. Also, the analysis of the models can be useful to define an optimal bed-temperature profile that improves the solid-state fermentation.