Modeling, Simulation and Optimized Design of a Microreactor for a Two‐Step Reaction

Chen, X.; Zeng, Hong; Wang, H.; Zhang, D.

doi:10.1002/ceat.201200058

Cited by 9 publications

(2 citation statements)

References 9 publications

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“…Its composition is varied and complicated relatively, usually including microelectrodes and sensitive magnet microdetector into chips. Accordingly, the active micromixer will be destined to meet some complex difficulties to overcome during multiple design, development, and production process . Compared with the active micromixer, the passive micromixer demands a much easier manufacturing condition because it does not require external energy for hydrodynamic driving control .…”

Section: Introductionmentioning

confidence: 99%

A novel passive micromixer with modified asymmetric lateral wall structures

Wang

Shi

Zhou

et al. 2018

Asia-Pacific J Chem Eng

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Homogeneous and rapid mixing in microfluidic devices have always been the premise requirement due to its integration with bioengineering and chemical experiments. In this work, a novel passive micromixer with modified asymmetric lateral wall structures is designed. The numerical simulation is carried out at the Reynolds number ranging from 0.1 to 100 for the novel microchannel and the ordinary "S"-shaped microchannel. The results indicate that, compared with the "S"-shaped micromixer, the novel structure exhibits superior mixing performance, which can be attributed to the increasing inertial effect and formation of secondary flow. The simulation results suggest that the novel micromixer developed here will achieve an efficient mixing performance.

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Section: Introductionmentioning

confidence: 99%

A novel passive micromixer with modified asymmetric lateral wall structures

Wang

Shi

Zhou

et al. 2018

Asia-Pacific J Chem Eng

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“…For example, silver nanoparticle formation in a microreactor was modeled using a reaction model coupled with computational fluid dynamics (CFD) and population balance equations (PBEs) . In another article, a two‐step microreactor for the investigation of glucose oxidation was modeled and optimized .…”

Section: Introductionmentioning

confidence: 99%

Optimization of Continuous Synthesis of Cross‐Linked Chitosan Nanoparticles Using Microreactors

Rathi

Gaikar

2017

Chem Eng & Technol

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A process for continuous synthesis of cross‐linked chitosan‐sodium tripolyphosphate (CS‐TPP) nanoparticles is optimized using microreactors for its comparison with a batch stirred reactor. The effect of various parameters including residence time, concentration of CS, pH of the CS solutions, and stabilizing surfactant concentration was modeled by population balance equations (PBEs) to determine size, growth, and nucleation rates of the CS‐TPP nanoparticles. The smallest particle size was obtained at lower residence time, lower concentration of CS, pH 5, and using a surfactant concentration above its critical micellar concentration. The particles obtained from the microreactors are agglomerated but are smaller in size as compared to those obtained from the batch reactor. The system was also optimized for the minimum particle size applying the estimated growth rate and the PBEs.

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Strategy for Scaling‐up of a Microsieve Dispersion Reactor

2014

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For the application of microreactors in industrial processes, more scaling‐up strategies are still required except of the original concept, the numbering‐up. A more maneuverable and economic approach, combining both similarity‐up and numbering‐up, is introduced as an example for an innovative strategy. CFD simulation is also applied to assist analysis and optimization of fluid distribution. Based on this concept, named similarity‐up + numbering‐up + simulation, a pilot‐plant microsieve dispersion minireactor used to proceed the reaction of cyclohexanecarboxylic acid and oleum is designed and tested experimentally. With the contribution of similarity‐up, the treating capacity of the core unit is significantly increased. Ten parallel units are integrated to form a correspondingly enhanced capacity of the microreactor which exhibits low pressure drop, stable operating performance, and excellent main product selectivity.

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Modeling, Simulation and Optimized Design of a Microreactor for a Two‐Step Reaction

Cited by 9 publications

References 9 publications

A novel passive micromixer with modified asymmetric lateral wall structures

A novel passive micromixer with modified asymmetric lateral wall structures

Optimization of Continuous Synthesis of Cross‐Linked Chitosan Nanoparticles Using Microreactors

Strategy for Scaling‐up of a Microsieve Dispersion Reactor

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