Modeling terahertz heating effects on water

Kristensen, Torben; Withayachumnankul, Withawat; Jepsen, Peter Uhd; Abbott, Derek

doi:10.1364/oe.18.004727

Cited by 58 publications

(53 citation statements)

References 30 publications

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“…Computational M&S techniques are incredibly valuable tools, which are finding increased use in THz biological research. For example, these tools are commonly used to determine field distribution in biological materials, to calculate the expected temperature rise during THz exposures, and to predict tissue damage thresholds [121,122,147,148]. There are many different types of modeling techniques, but the most commonly used methods are FDTD, Finite Element method (FEM), Finite Difference, and Monte Carlo.…”

Section: Equipment Used For Controlled Exposures and Accurate Dosimetrymentioning

confidence: 99%

Invited Review Article: Current State of Research on Biological Effects of Terahertz Radiation

Wilmink

Grundt

2011

J Infrared Milli Terahz Waves

277

186

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In recent years, terahertz radiation sources are increasingly being exploited in military and civil applications. However, only a few studies have so far been conducted to examine the biological effects associated with terahertz radiation. In this study, we evaluated the cellular response of mesenchymal mouse stem cells exposed to THz radiation. We apply low-power radiation from both a pulsed broad-band (centered at 10 THz) source and from a CW laser (2.52 THz) source. Modeling, empirical characterization, and monitoring techniques were applied to minimize the impact of radiation-induced increases in temperature. qRT-PCR was used to evaluate changes in the transcriptional activity of selected hyperthermic genes. We found that temperature increases were minimal, and that the differential expression of the investigated heat shock proteins (HSP105, HSP90, and CPR) was unaffected, while the expression of certain other genes (Adiponectin, GLUT4, and PPARG) showed clear effects of the THz irradiation after prolonged, broad-band exposure.

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Section: Equipment Used For Controlled Exposures and Accurate Dosimetrymentioning

confidence: 99%

Invited Review Article: Current State of Research on Biological Effects of Terahertz Radiation

Wilmink

Grundt

2011

J Infrared Milli Terahz Waves

277

186

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“…In accordance with international safety guidelines moderate exposure to THz radiation is safe [44] and it doesn't heat the sample or cause damage [45]. The other nondestructive methods commonly used for sub-surface imaging in art and archaeology (X-ray, γ-ray, protons and neutrons) are ionizing and consequently their accessibility is limited.…”

Section: Safementioning

confidence: 99%

Terahertz and Cultural Heritage Science: Examination of Art and Archaeology

Cosentino¹

2016

Technologies

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Cultural Heritage scientists need methodologies to examine Art and Archaeology in order to understand artistic materials and techniques and devise better conservation procedures. This review discusses the most successful and promising applications of Terahertz (THz) technology in Cultural Heritage Science. THz is used in homeland security and for plenty of other industrial sectors and it presents a number of valuable features specifically for the investigation of Art and Archaeology: No radiation risk, low power, non-contact and reflection mode. Recent technical advancements are also making its application fast, mobile and relatively affordable creating a potential for its diffused implementation in museums. While THz is most promising for the investigation of multilayered art, such as paintings, it has been tested on a very large range of artifacts, from manuscripts to mummies and lacquered historical furniture.

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“…Previous bio-related studies conducted by "THz-BRIDGE " project [8] found that THz-induced bio-effects were primarily mediated by thermal mechanisms, mainly accounting that water is the solvent for all biological entities and strongly absorbe THz radiation and that the energy of THz photons is not high enough to directly disrupt chemical bonds. Kristensen etc applied Kirchhoff's heat equation to model the influence of a CW terahertz beam on a sample of water; they found that the steady-state temperature increase of transmitted power was 1.8°C/mW [9]. If a sufficient-time exposure of THz beam (CW, over 0.56mW) was maintained to thermal equilibrium, a temperature increase of 30°C for a spot diameter of 0.5mm could be realized.…”

Section: A Thermal Effectsmentioning

confidence: 99%

An overview of cancer treatment by terahertz radiation

Wang

Yang

et al. 2013

2013 IEEE MTT-S International Microwave Workshop Series on RF and Wireless Technologies for Biomedical and Healthcare Applicati

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Cancer Cancer Cancer Cancer claimed claimed claimed claimed the the the the death death death death of of of of over over over over 7.6 7.6 7.6 7.6 million million million million people people people people each each each each year year year year all all all all over over over over the the the the world. world. world. world. Many Many Many Many attempts attempts attempts attempts have have have have being being being being practiced practiced practiced practiced in in in in clinical clinical clinical clinical applications, applications, applications, applications, yet yet yet yet some some some some new new new new technologies technologies technologies technologies are are are are believed believed believed believed to to to to make make make make up up up up for for for for the the the the shortcomings shortcomings shortcomings shortcomings of of of of existing existing existing existing methods. methods. methods. methods.

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Modeling terahertz heating effects on water

Cited by 58 publications

References 30 publications

Invited Review Article: Current State of Research on Biological Effects of Terahertz Radiation

Invited Review Article: Current State of Research on Biological Effects of Terahertz Radiation

Terahertz and Cultural Heritage Science: Examination of Art and Archaeology

An overview of cancer treatment by terahertz radiation

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