Abstract. This paper uses the LS-DYNA and MSC. DYTRAN to generate a three-dimensional numerical simulation model of shallow water explosion respectively, achieves a effective simulation of fluid-structure interaction in multi-material media, and simulates the bubble pulsation and propagation of impact wave caused by shallow water explosion. By validating the creditability of the model through comparing simulation results with the formula of empirical formula, and by analyzing the load characteristic and distribution of underwater explosive, this paper develops the following conclusions as follows. MSC. DYTRAN has a stronger capacity in boundary setting and fluid-solid coupling, therefore the bubble pulsation rate and periodic attenuation are faster and maximum radius is bigger in its simulation. There are different bubble scattering morphology on the two simulations, futher experiments are needed to verify that. The reflection effect of water bottom is stronger in LS-DYNA; the simulation effects are better for the peak pressure of shock wave loading and the specific impulse of bubble pulsation loading; the simulation is more accurate for the peak pressure of bubble pulsation loading and the specific impulse of shock wave loading in LS-DYNA.