Modeling the rabbit's eye with the Mueller matrix for birefringent properties

Abstract

The effect of changing corneal birefringence, due to motion artifact, remains a major obstacle to the development of an accurate non-invasive polarimetric glucose sensor for patients with diabetes mellitus. Consequently, there is still a need to characterize fully, and to quantify the relative changes in corneal birefringence to facilitate the optimization of detection algorithms, enabling in vivo accuracy within 10mg/dl. In this paper, we present preliminary results, utilizing a Mueller matrix imaging technique, that demonstrates notable relative changes in the apparent retardance and in the apparent fast axis location of rabbit cornea.