2024
DOI: 10.1038/s41598-024-73164-7
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Modeling transmission mechanism to infer treatment efficacy of different drugs and combination therapy against Trichuris trichiura

Carla M. Grolimund,
Jürg Utzinger,
Jean T. Coulibaly
et al.

Abstract: Trichuris trichiura is one of four soil-transmitted helminth species that, collectively, are responsible for a considerable public health burden. The World Health Organization recommends preventive chemotherapy as the main intervention to eliminate soil-transmitted helminthiasis as a public health problem. Clinical trials estimated the efficacy of different drugs and treatment regimen against T. trichiura and other soil-transmitted helminth species, whilst meta-analyses and mo… Show more

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